SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression. - Wikidata - awgldk - TriplyDB

SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression.

SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression.

http://www.wikidata.org/entity/Q36868674

about

Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcription Extended wakefulness: compromised metabolics in and degeneration of locus ceruleus neurons SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress Short-term calorie restriction enhances skeletal muscle stem cell function Mitophagy plays a central role in mitochondrial ageing Sirt1 and the Mitochondria Redox regulation of FoxO transcription factors Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration Sirtuin 1 and sirtuin 3: physiological modulators of metabolism Role of sirtuins in ischemia-reperfusion injury SIRT3 regulates progression and development of diseases of aging.Sirtuins in hematological aging and malignancy Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake Mitochondrial stress signaling promotes cellular adaptations Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis Mitochondrial localization of the forkhead box class O transcription factor FOXO3a in brain FoxO3a governs early microglial proliferation and employs mitochondrial depolarization with caspase 3, 8, and 9 cleavage during oxidant induced apoptosis.Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle FOXO3a governs early and late apoptotic endothelial programs during elevated glucose through mitochondrial and caspase signaling.Characterization of the murine SIRT3 mitochondrial localization sequence and comparison of mitochondrial enrichment and deacetylase activity of long and short SIRT3 isoforms SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient- and exercise-induced stress.Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis.SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulin-stimulated glucose uptake in mice Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition.SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis.SirT3 regulates the mitochondrial unfolded protein response.Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress.Mitochondrial acetylation and diseases of aging.Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning.Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress.Angiotensin receptors as determinants of life span.Glutathione suppresses cerebral infarct volume and cell death after ischemic injury: involvement of FOXO3 inactivation and Bcl2 expression.AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD The human sirtuin family: evolutionary divergences and functions.Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart

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P2860

SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression.

http://www.wikidata.org/entity/Q36868674

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

SIRT3 interacts with the daf-1 ...... O3a dependent gene expression.

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type

label

SIRT3 interacts with the daf-1 ...... O3a dependent gene expression.

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prefLabel

SIRT3 interacts with the daf-1 ...... O3a dependent gene expression.

@en

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International Journal of Biological Sciences

P1476

SIRT3 interacts with the daf-1 ...... O3a dependent gene expression.

@en

P2093

Bong-Hyun Ahn

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Chu-Xia Deng

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David Gius

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Douglas R Spitz

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Hyun-Seok Kim

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J Daniel Pennington

http://www.w3.org/2001/XMLSchema#string

Jaime Leclerc

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Kheem S Bisht

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Kristi Muldoon Jacobs

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Lunching Sun

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P2860

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress

p53 regulates mitochondrial respiration

The human cytochrome c oxidase assembly factors SCO1 and SCO2 have regulatory roles in the maintenance of cellular copper homeostasis

Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

Cell cycle and death control: long live Forkheads

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

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291-299

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10.7150/IJBS.4.291

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P433

5

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4

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2008-09-05T00:00:00Z

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18781224

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2532794

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