Bcl-2-regulated apoptosis: mechanism and therapeutic potential
about
Titanium dioxide (TiO2) nanoparticles preferentially induce cell death in transformed cells in a Bak/Bax-independent fashionMitochondrial BCL-2 inhibits AMBRA1-induced autophagyNoxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cellsHistone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIPThe hepatitis C virus core protein contains a BH3 domain that regulates apoptosis through specific interaction with human Mcl-1Bcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpointsCHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stressApolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell deathDocosahexaenoic Acid Induces Oxidative DNA Damage and Apoptosis, and Enhances the Chemosensitivity of Cancer CellsPotential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?Regulation of Bim in Health and DiseaseThe eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral InfectionsAdvances in astrocyte-targeted approaches for stroke therapy: an emerging role for mitochondria and microRNASESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the questionEvidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAXTargeting Glial Mitochondrial Function for Protection from Cerebral Ischemia: Relevance, Mechanisms, and the Role of MicroRNAsHypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domainsAuto-FACE: an NMR based binding site mapping program for fast chemical exchange protein-ligand systemsCyclosporin A induces apoptosis in H9c2 cardiomyoblast cells through calcium-sensing receptor-mediated activation of the ERK MAPK and p38 MAPK pathways14-3-3theta protects against neurotoxicity in a cellular Parkinson's disease model through inhibition of the apoptotic factor BaxActive fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergenceRole of autophagy in cancerTherapeutic ultrasound protects HUVECs from ischemia/hypoxia-induced apoptosis via the PI3K-Akt pathwayCancer Therapy Due to Apoptosis: Galectin-9.Salvianolic acid B attenuates oxidized low-density lipoprotein-induced endothelial cell apoptosis through inhibition of oxidative stress, p53, and caspase-3 pathways.Why do cancer cells become "addicted" to oncogenic epidermal growth factor receptor?BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-XL (BCL2L1).Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process.Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer modelRole of the translocation partner in protection against AID-dependent chromosomal translocationsEctopic overexpression of LAPTM5 results in lysosomal targeting and induces Mcl-1 down-regulation, Bak activation, and mitochondria-dependent apoptosis in human HeLa cells.Expression of human Bcl-xL (Ser49) and (Ser62) mutants in Caenorhabditis elegans causes germline defects and aneuploidy.Spontaneously immortalised bovine mammary epithelial cells exhibit a distinct gene expression pattern from the breast cancer cellsInvolvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells.The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damagePyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo.A novel ADOA-associated OPA1 mutation alters the mitochondrial function, membrane potential, ROS production and apoptosis.Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1
P2860
Q21133813-F3DD6C12-A22D-43BA-A8C3-58CA2E3C497DQ24294358-21CF0A30-1EEB-4D13-AD24-FD2CEF07B9B6Q24298561-06E7D825-8E6E-4960-B090-0A0BDAB85163Q24302531-E5649CEF-3375-4781-8A2C-B70B23B9939FQ24314941-7429EE0D-6264-4E06-A1B8-4D34A968D30BQ24322034-A17086F7-8694-4723-AE3B-245327F84DD3Q24339500-977FC67E-50C9-43E1-B0B4-7B0ADCFBCFC5Q24652950-57B93F80-6CE2-4090-A110-5BDBB585CC49Q26741436-13C6A66D-0312-40B9-8126-1E4D66048232Q26771601-F4B40D43-DC20-4269-A0C0-65BAB1C262F9Q26781203-92E358BC-3E84-4293-A3ED-48AF30C549D1Q26825635-C9E9EF7F-059F-4A2A-ACFA-0242D3BB542FQ26827622-C3FADD81-5334-4B7E-94CC-ABA683A59BCAQ27011691-BF850AEC-7275-4B5A-9CAD-13C712B330FAQ27665695-DFCD3994-89AC-4615-9738-633F430EA082Q28079891-2C37934A-E29E-4266-A190-2E9B4E981E20Q28114920-96D6DB2C-8B19-4CF3-BDE4-F6E131C7FF48Q28472946-0C0266C4-CB00-47CD-88CA-EF6D57097177Q28584308-693C4309-0EFD-4F84-ADCF-A2C89DBF694BQ28742388-2DA8C237-60F1-4C3D-99C1-967F24F7294DQ28749082-4C39BC36-6F98-49F0-B2BA-F84E2324AD09Q29620348-3865EC4D-5F87-4DE5-ACA1-6B20E399443BQ30357237-8F039567-C9DB-4E14-9F06-7C1B8407A169Q30397015-2C2416CD-D289-47E5-8FC9-7A9399404D72Q32182908-1F9B698E-AE08-4915-B982-2D242AC26E8AQ33304557-29F6180A-FBF8-4B92-9669-7B2BB811B088Q33394363-91FEEC48-2039-4B37-8E3C-9FEAF52828BDQ33432478-0BDABFCA-53AC-427B-B031-107F792D88E4Q33569749-D99CAB4C-6023-4AA0-963B-F0DD7AF4AD4BQ33575434-C077746E-93C4-444D-9FA0-9D0761FC28E8Q33591714-383688C8-0D04-4A26-B8DF-685BE70201D5Q33626463-135426BD-1F25-4255-B3F4-1A40C1E92CABQ33648335-82EC9F65-C541-4DE6-BEEC-86B8DB991F64Q33726206-8C84A869-A4C7-4DFE-8C72-39E84EF014FCQ33776998-3FF9B84F-0355-4183-BBC9-E07558538405Q33793022-715A8BCB-C20B-46E9-9C1E-3F64F81E0D4AQ33832757-C21749B4-1FEF-4A6D-9B05-24A3850BB890Q33833120-2FC24EA1-E013-4F0D-87EA-DBCFC89B5EFCQ33916058-7D86CF27-0E3A-4C60-A604-853ED809EB59Q33924886-5077AE99-BF71-4919-A11E-C8016DB2546D
P2860
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
@en
type
label
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
@en
prefLabel
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
@en
P2860
P1476
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
@en
P2093
Jerry M Adams
P2860
P304
P356
10.1016/J.COI.2007.05.004
P577
2007-07-12T00:00:00Z