Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells.
about
Regulation of alternative splicing by SRrp86 and its interacting proteinsA novel SR-related protein is required for the second step of Pre-mRNA splicingMolecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformationIdentification and characterization of three members of the human SR family of pre-mRNA splicing factorsA region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasisFunctional association of human Ki-1/57 with pre-mRNA splicing eventsIdentification and characterization of a novel serine-arginine-rich splicing regulatory proteinRole of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein.E1A promotes association between p300 and pRB in multimeric complexes required for normal biological activityIdentification of a novel E1A response element in the mouse c-fos promoter.Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein.Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein.Glucocorticoids facilitate the stable transformation of embryonal rat fibroblasts by a polyomavirus large tumor antigen-deficient mutant.Induction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.Differential splicing yields novel adenovirus 5 E1A mRNAs that encode 30 kd and 35 kd proteins.A novel adenovirus-2 E1A mRNA encoding a protein with transcription activation properties.Adenovirus E1A gene autorepression: revertants of an E1A promoter mutation encode altered E1A proteins.The CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation.Growth factor(s) produced during infection with an adenovirus variant stimulates proliferation of nonestablished epithelial cells.Mechanisms of oncogene cooperation: activation and inactivation of a growth antagonist.New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicingFunctions of the two adenovirus early E1A proteins and their conserved domains in cell cycle alteration, actin reorganization, and gene activation in rat cells.DNA-binding properties of an adenovirus 289R E1A proteinRole of the modular domains of SR proteins in subnuclear localization and alternative splicing specificityIdentification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growthThe adenovirus E1A 12S product displays functional redundancy in activating the human proliferating cell nuclear antigen promoterThe adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2.The E1A products of oncogenic adenovirus serotype 12 include amino-terminally modified forms able to bind the retinoblastoma protein but not p300Induction of gene expression by exon 2 of the major E1A proteins of adenovirus type 5.The amino-terminal portion of CD1 of the adenovirus E1A proteins is required to induce susceptibility to tumor necrosis factor cytolysis in adenovirus-infected mouse cellsAnti-adenovirus type 5 cytotoxic T lymphocytes: immunodominant epitopes are encoded by the E1A gene.Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene productsAdenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins.Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen.Adenovirus E1A makes two distinct contacts with the retinoblastoma protein.E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products.Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1aAnalysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activityDifferential requirement for adenovirus type 12 E1A gene products in oncogenic transformation.Interactions between cell growth-regulating domains in the products of the adenovirus E1A oncogene.
P2860
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P2860
Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Adenovirus E1A coding sequence ...... nsform cultured primary cells.
@en
type
label
Adenovirus E1A coding sequence ...... nsform cultured primary cells.
@en
prefLabel
Adenovirus E1A coding sequence ...... nsform cultured primary cells.
@en
P2093
P2860
P356
P1476
Adenovirus E1A coding sequence ...... nsform cultured primary cells.
@en
P2093
P2860
P304
P356
10.1128/MCB.6.3.887
P407
P577
1986-03-01T00:00:00Z