Molecular genetic analysis of a vaccinia virus gene with an essential role in DNA replication
about
Members of a novel family of mammalian protein kinases complement the DNA-negative phenotype of a vaccinia virus ts mutant defective in the B1 kinaseOrigin-independent plasmid replication occurs in vaccinia virus cytoplasmic factories and requires all five known poxvirus replication factorsClustered charge-to-alanine mutagenesis of the vaccinia virus H5 gene: isolation of a dominant, temperature-sensitive mutant with a profound defect in morphogenesisRole of vaccinia virus A20R protein in DNA replication: construction and characterization of temperature-sensitive mutants.The A20R protein is a stoichiometric component of the processive form of vaccinia virus DNA polymeraseBiochemical and genetic analysis of the vaccinia virus d5 protein: Multimerization-dependent ATPase activity is required to support viral DNA replicationThe vaccinia virus D5 protein, which is required for DNA replication, is a nucleic acid-independent nucleoside triphosphatase.Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens.Molecular genetic and biochemical characterization of the vaccinia virus I3 protein, the replicative single-stranded DNA binding protein.Cytoplasmic ATR Activation Promotes Vaccinia Virus Genome ReplicationDNA strand exchange catalyzed by proteins from vaccinia virus-infected cells.Genetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.Vaccinia virus nucleoside triphosphate phosphohydrolase I controls early and late gene expression by regulating the rate of transcription.Transient expression of the vaccinia virus DNA polymerase is an intrinsic feature of the early phase of infection and is unlinked to DNA replication and late gene expression.Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.Vaccinia virus B1 kinase: phenotypic analysis of temperature-sensitive mutants and enzymatic characterization of recombinant proteins.Molecular genetic analysis of vaccinia virus DNA polymerase mutants.Temperature-sensitive vaccinia virus mutants identify a gene with an essential role in viral replication.Identification of the vaccinia virus gene encoding an 18-kilodalton subunit of RNA polymerase and demonstration of a 5' poly(A) leader on its early transcript.Vaccinia virus DNA replication: two hundred base pairs of telomeric sequence confer optimal replication efficiency on minichromosome templates.Characterization of the single-stranded DNA binding protein encoded by the vaccinia virus I3 gene.Genetic Confirmation that the H5 Protein Is Required for Vaccinia Virus DNA Replication.Barrier to autointegration factor (BAF) inhibits vaccinia virus intermediate transcription in the absence of the viral B1 kinase.Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity.Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir.Temperature-sensitive mutants with lesions in the vaccinia virus F10 kinase undergo arrest at the earliest stage of virion morphogenesis.The vaccinia virus gene I2L encodes a membrane protein with an essential role in virion entry.Identification and characterization of an extracellular envelope glycoprotein affecting vaccinia virus egress.Comparative whole genome sequence analysis of wild-type and cidofovir-resistant monkeypoxvirus.Suppressors of a host range mutation in the rabbitpox virus serpin SPI-1 map to proteins essential for viral DNA replication.
P2860
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P2860
Molecular genetic analysis of a vaccinia virus gene with an essential role in DNA replication
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Molecular genetic analysis of ...... ential role in DNA replication
@en
type
label
Molecular genetic analysis of ...... ential role in DNA replication
@en
prefLabel
Molecular genetic analysis of ...... ential role in DNA replication
@en
P2860
P1433
P1476
Molecular genetic analysis of ...... ential role in DNA replication
@en
P2093
P2860
P304
P407
P577
1987-10-01T00:00:00Z