The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis
about
TMC207: the first compound of a new class of potent anti-tuberculosis drugsThe mechanism of action of PA-824: Novel insights from transcriptional profilingThe emerging role of gasotransmitters in the pathogenesis of tuberculosisNext-generation antimicrobials: from chemical biology to first-in-class drugsNitroimidazoles for the treatment of TB: past, present and futureMycobacterium tuberculosis: success through dormancyRedox homeostasis in mycobacteria: the key to tuberculosis control?Structure of the mycobacterial ATP synthase Fo rotor ring in complex with the anti-TB drug bedaquiline.The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substratesVariations of Subunit of the Mycobacterium tuberculosis F1Fo ATP Synthase and a Novel Model for Mechanism of Action of the Tuberculosis Drug TMC207Mycobacterium tuberculosis Rv3406 is a type II alkyl sulfatase capable of sulfate scavengingA new type of Na(+)-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motifStructure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generationFirst-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosisProbing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthaseMetabolic regulation of mycobacterial growth and antibiotic sensitivityIdentification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrBDosS responds to a reduced electron transport system to induce the Mycobacterium tuberculosis DosR regulonNitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stressesMycobacterium tuberculosis MT2816 encodes a key stress-response regulatorBiochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetaseCharacterization of a Clp protease gene regulator and the reaeration response in Mycobacterium tuberculosisLoss of kinase activity in Mycobacterium tuberculosis multidomain protein Rv1364cStabilization of homoserine-O-succinyltransferase (MetA) decreases the frequency of persisters in Escherichia coli under stressful conditionsComparative Proteomic Analysis of Aminoglycosides Resistant and Susceptible Mycobacterium tuberculosis Clinical Isolates for Exploring Potential Drug TargetsIon Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosisMechanisms of Pyrazinamide Action and ResistanceThe spectrum of latent tuberculosis: rethinking the biology and intervention strategiesDiscovery of Q203, a potent clinical candidate for the treatment of tuberculosis.Recent advances in tuberculosis: New drugs and treatment regimens.Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm.Metabolic Perspectives on PersistenceNewer antibacterial drugs for a new century.Simple model for testing drugs against nonreplicating Mycobacterium tuberculosisDelayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism.Fumarate reductase activity maintains an energized membrane in anaerobic Mycobacterium tuberculosis.Polymyxin B identified as an inhibitor of alternative NADH dehydrogenase and malate: quinone oxidoreductase from the Gram-positive bacterium Mycobacterium smegmatis.The type I NADH dehydrogenase of Mycobacterium tuberculosis counters phagosomal NOX2 activity to inhibit TNF-alpha-mediated host cell apoptosis.Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazinesExploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
P2860
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P2860
The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The protonmotive force is requ ...... ing Mycobacterium tuberculosis
@en
type
label
The protonmotive force is requ ...... ing Mycobacterium tuberculosis
@en
prefLabel
The protonmotive force is requ ...... ing Mycobacterium tuberculosis
@en
P2093
P2860
P356
P1476
The protonmotive force is requ ...... ing Mycobacterium tuberculosis
@en
P2093
Kevin Pethe
Lucinda Rand
Srinivasa P S Rao
Sylvie Alonso
P2860
P304
11945-11950
P356
10.1073/PNAS.0711697105
P407
P50
P577
2008-08-12T00:00:00Z