Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.
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Exome sequencing identifies a novel missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegiaGenes and Pathways Involved in Adult Onset Disorders Featuring Muscle Mitochondrial DNA InstabilityMitochondrial DNA depletion syndromes: review and updates of genetic basis, manifestations, and therapeutic optionsLimited dCTP availability accounts for mitochondrial DNA depletion in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progressionMolecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductaseVaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis.Pathomechanisms in coenzyme q10-deficient human fibroblasts.Identification and characterization of alternative promoters, transcripts and protein isoforms of zebrafish R2 gene.Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphateRegulation and functional contribution of thymidine kinase 1 in repair of DNA damageRibonucleotide reductase small subunit M2B prognoses better survival in colorectal cancerNucleotide excision repair efficiency in quiescent human fibroblasts is modulated by circadian clockIn vivo function of the murid herpesvirus-4 ribonucleotide reductase small subunit.Deoxynucleoside salvage facilitates DNA repair during ribonucleotide reductase blockade in human cervical cancersA functional approach reveals a genetic and physical interaction between ribonucleotide reductase and CHK1 in mammalian cells.Ribonucleotide reductase subunit M2 predicts survival in subgroups of patients with non-small cell lung carcinoma: effects of gender and smoking statusSinglet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication.Ribonucleotide reductase as one important target of [Tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772).Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamersMammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cellsRNase H2-initiated ribonucleotide excision repair.Elevated ribonucleotide reductase levels associate with suppressed radiochemotherapy response in human cervical cancers.PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.Ribonucleotide reductase small subunit M2 serves as a prognostic biomarker and predicts poor survival of colorectal cancers.miR-8-3p regulates mitoferrin in the testes of Bactrocera dorsalis to ensure normal spermatogenesisRibonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysisInhibition of DNA synthesis facilitates expansion of low-complexity repeats: is strand slippage stimulated by transient local depletion of specific dNTPs?A heterozygous truncating mutation in RRM2B causes autosomal-dominant progressive external ophthalmoplegia with multiple mtDNA deletions.Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks.Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductaseTrafficking of intracellular folates.Targeting ribonucleotide reductase for cancer therapy.Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies.Deoxyribonucleotide metabolism, mutagenesis and cancer.Mitochondrial purine and pyrimidine metabolism and beyond.A Critical Balance: dNTPs and the Maintenance of Genome StabilitySynthesis of mitochondrial DNA precursors during myogenesis, an analysis in purified C2C12 myotubes.Sensitizing cancer cells: is it really all about U?Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase.
P2860
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P2860
Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Ribonucleotide reduction is a ...... s independently of DNA damage.
@en
type
label
Ribonucleotide reduction is a ...... s independently of DNA damage.
@en
prefLabel
Ribonucleotide reduction is a ...... s independently of DNA damage.
@en
P2093
P2860
P356
P1476
Ribonucleotide reduction is a ...... s independently of DNA damage.
@en
P2093
Artur Fijolek
Chiara Rampazzo
Giovanna Pontarin
Lars Thelander
Paola Ferraro
Paola Pizzo
Peter A Reichard
Tullio Pozzan
Vera Bianchi
P2860
P304
17801-17806
P356
10.1073/PNAS.0808198105
P407
P577
2008-11-07T00:00:00Z