Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.
about
Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formationUbiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradationThe life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathGene overexpression: uses, mechanisms, and interpretationStructure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13The Yeast E4 Ubiquitin Ligase Ufd2 Interacts with the Ubiquitin-like Domains of Rad23 and Dsk2 via a Novel and Distinct Ubiquitin-like Binding DomainStructural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporationDisassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome.A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasomeRegulation of proteasome activity in health and diseaseRecognition and processing of ubiquitin-protein conjugates by the proteasomeUbiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting.A genome-wide synthetic dosage lethality screen reveals multiple pathways that require the functioning of ubiquitin-binding proteins Rad23 and Dsk2Molecular mechanisms of proteasome plasticity in aging.Assembly, structure, and function of the 26S proteasome.VWA domain of S5a restricts the ability to bind ubiquitin and Ubl to the 26S proteasome.Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals.Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3Base-CP proteasome can serve as a platform for stepwise lid formationExtended ubiquitin species are protein-based DUB inhibitors.APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasomeThe ubiquitin-proteasome system of Saccharomyces cerevisiae.Ubiquitin receptors and protein quality controlUbiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtinUBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranesProteomics to study the diversity and dynamics of proteasome complexes: from fundamentals to the clinic.Structural disorder and its role in proteasomal degradation.Tuning the proteasome to brighten the end of the journey.The deubiquitylating enzyme Ubp12 regulates Rad23-dependent proteasomal degradation.Polyubiquitin-Photoactivatable Crosslinking Reagents for Mapping Ubiquitin Interactome Identify Rpn1 as a Proteasome Ubiquitin-Associating Subunit.A reduced VWA domain-containing proteasomal ubiquitin receptor of Giardia lamblia localizes to the flagellar pore regions in microtubule-dependent manner.Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome.Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.BAG6 regulates the quality control of a polytopic ERAD substrate.S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains
P2860
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P2860
Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Extraproteasomal Rpn10 restric ...... ng protein Dsk2 to proteasome.
@en
Extraproteasomal Rpn10 restric ...... ng protein Dsk2 to proteasome.
@nl
type
label
Extraproteasomal Rpn10 restric ...... ng protein Dsk2 to proteasome.
@en
Extraproteasomal Rpn10 restric ...... ng protein Dsk2 to proteasome.
@nl
prefLabel
Extraproteasomal Rpn10 restric ...... ng protein Dsk2 to proteasome.
@en
Extraproteasomal Rpn10 restric ...... ng protein Dsk2 to proteasome.
@nl
P2093
P2860
P50
P1433
P1476
Extraproteasomal Rpn10 restric ...... ing protein Dsk2 to proteasome
@en
P2093
Arun Dakshinamurthy
Oded Kleifeld
Yulia Matiuhin
P2860
P304
P356
10.1016/J.MOLCEL.2008.10.011
P577
2008-11-01T00:00:00Z