APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1 - Wikidata - awgldk - TriplyDB

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

http://www.wikidata.org/entity/Q35754866

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The recognition of ubiquitinated proteins by the proteasome RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination Functions of the 19S complex in proteasomal degradation Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins Regulation of proteasome activity in health and disease Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.Paradigms of protein degradation by the proteasome.RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex Substrate degradation by the proteasome: a single-molecule kinetic analysis.An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination Gates, Channels, and Switches: Elements of the Proteasome Machine Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin Chains.The ubiquitin-proteasome system of Saccharomyces cerevisiae.Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron Design principles of a universal protein degradation machine.An E2 enzyme Ubc11 is required for ubiquitination of Slp1/Cdc20 and spindle checkpoint silencing in fission yeast USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites.The Anaphase-Promoting Complex (APC) ubiquitin ligase affects chemosensory behavior in C. elegans.Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid.Conserved Sequence Preferences Contribute to Substrate Recognition by the Proteasome.Monoubiquitination in proteasomal degradation.Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20 Using the ubiquitin-modified proteome to monitor protein homeostasis function.p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair.Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein.The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore.Panta rhei: the APC/C at steady state.Measuring APC/C-Dependent Ubiquitylation In Vitro.Pushing the Boundaries of Chemical Protein Synthesis: The Case of Ubiquitin Chains and Polyubiquitinated Peptides and Proteins.The fine-tuning of proteolytic pathways in Alzheimer's disease.The increasing complexity of the ubiquitin code.The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity.Upregulated expression of ubiquitin-conjugating enzyme E2Q1 (UBE2Q1) is associated with enhanced cell proliferation and poor prognosis in human hapatocellular carcinoma.UBE2Q1 expression in human colorectal tumors and cell lines.Ubiquitination site preferences in anaphase promoting complex/cyclosome (APC/C) substrates.Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal.

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P2860

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

http://www.wikidata.org/entity/Q35754866

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年论文

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name

APC/C-mediated multiple monoub ...... gradation signal for cyclin B1

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APC/C-mediated multiple monoub ...... gradation signal for cyclin B1

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type

label

APC/C-mediated multiple monoub ...... gradation signal for cyclin B1

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APC/C-mediated multiple monoub ...... gradation signal for cyclin B1

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prefLabel

APC/C-mediated multiple monoub ...... gradation signal for cyclin B1

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APC/C-mediated multiple monoub ...... gradation signal for cyclin B1

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P1433

Nature Cell Biology

P1476

APC/C-mediated multiple monoub ...... gradation signal for cyclin B1

@en

P2093

Byung-Hoon Lee

http://www.w3.org/2001/XMLSchema#string

Daniel Finley

http://www.w3.org/2001/XMLSchema#string

Marie Lea Berkowitz

http://www.w3.org/2001/XMLSchema#string

Nathaniel A Hathaway

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Nevena V Dimova

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P2860

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage

Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.

Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin

The E3 ligase TRAF6 regulates Akt ubiquitination and activation

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis.

Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

Identification of a physiological E2 module for the human anaphase-promoting complex

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168-176

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scholarly article

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10.1038/NCB2425

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2

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14

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Donald S Kirkpatrick

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2012-01-29T00:00:00Z

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221785677

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22286100

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3278798

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