Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis - Wikidata - awgldk - TriplyDB

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis

http://www.wikidata.org/entity/Q37115208

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Enhancing diagnosis, prognosis, and therapeutic outcome prediction of gliomas using genomics SCCRO promotes glioma formation and malignant progression in mice Will kinase inhibitors make it as glioblastoma drugs?Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma Targeting autophagy to sensitive glioma to temozolomide treatment Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy Molecular imaging of EGFR/HER2 cancer biomarkers by protein MRI contrast agents Cell of origin for malignant gliomas and its implication in therapeutic development Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells.Functional delivery of siRNA in mice using dendriworms.Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.The pathobiology of glioma tumors The probable cell of origin of NF1- and PDGF-driven glioblastomas.Arginine-rich, cell penetrating peptide-anti-microRNA complexes decrease glioblastoma migration potential.EGFR variant-mediated invasion by enhanced CXCR4 expression through transcriptional and post-translational mechanisms.Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion.Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma Gene expression profiles of human glioblastomas are associated with both tumor cytogenetics and histopathology.Sexually dimorphic RB inactivation underlies mesenchymal glioblastoma prevalence in males PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease.Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression A mathematical framework to determine the temporal sequence of somatic genetic events in cancer Treatment of glioblastoma multiforme using a combination of small interfering RNA targeting epidermal growth factor receptor and β-catenin.What does physics have to do with cancer?Surprisal analysis of Glioblastoma Multiform (GBM) microRNA dynamics unveils tumor specific phenotype.Quantitative proteomic analysis reveals effects of epidermal growth factor receptor (EGFR) on invasion-promoting proteins secreted by glioblastoma cells.Gliomagenesis and the use of neural stem cells in brain tumor treatment Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process The role of sphingosine kinase-1 in EGFRvIII-regulated growth and survival of glioblastoma cells Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology?MicroRNA-146a inhibits glioma development by targeting Notch1 Whole genome sequencing of glioblastoma multiforme identifies multiple structural variations involved in EGFR activation Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms.Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase.Capturing the molecular and biological diversity of high-grade astrocytoma in genetically engineered mouse models Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition.

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Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis

http://www.wikidata.org/entity/Q37115208

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 February 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Oncogenic EGFR signaling coope ...... ene functions in gliomagenesis

@en

Oncogenic EGFR signaling coope ...... ne functions in gliomagenesis.

@nl

type

label

Oncogenic EGFR signaling coope ...... ene functions in gliomagenesis

@en

Oncogenic EGFR signaling coope ...... ne functions in gliomagenesis.

@nl

prefLabel

Oncogenic EGFR signaling coope ...... ene functions in gliomagenesis

@en

Oncogenic EGFR signaling coope ...... ne functions in gliomagenesis.

@nl

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PNAS.0813314106

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Oncogenic EGFR signaling coope ...... ene functions in gliomagenesis

@en

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Abraham Boskovitz

http://www.w3.org/2001/XMLSchema#string

Al Charest

http://www.w3.org/2001/XMLSchema#string

David E Housman

http://www.w3.org/2001/XMLSchema#string

Haihao Zhu

http://www.w3.org/2001/XMLSchema#string

Jaime Acquaviva

http://www.w3.org/2001/XMLSchema#string

John W Chen

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Pranatartiharan Ramachandran

http://www.w3.org/2001/XMLSchema#string

Roderick T Bronson

http://www.w3.org/2001/XMLSchema#string

Rolf Pfannl

http://www.w3.org/2001/XMLSchema#string

Steve Woolfenden

http://www.w3.org/2001/XMLSchema#string

P2860

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Defining the role of mTOR in cancer

Upstream and downstream of mTOR

Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy.

PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors.

Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma.

The complexity of targeting EGFR signalling in cancer: from expression to turnover.

Dynamic control of signaling by modular adaptor proteins.

Structural alterations of the epidermal growth factor receptor gene in human gliomas

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2712-2716

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scholarly article

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10.1073/PNAS.0813314106

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8

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106

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Ralph Weissleder

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2009-02-05T00:00:00Z

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23983329

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19196966

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2650331

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