Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells - Wikidata - awgldk - TriplyDB

Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells

Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells

http://www.wikidata.org/entity/Q37131331

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The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor.Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolution Molecular composition of staufen2-containing ribonucleoproteins in embryonic rat brain Extracellular Signal-regulated Kinase (ERK)-dependent Phosphorylation of Y-Box-binding Protein 1 (YB-1) Enhances Gene Expression in Granulosa Cells in Response to Follicle-stimulating Hormone (FSH)RSK in tumorigenesis: connections to steroid signaling.Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer.YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance.Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer.Calcineurin-mediated YB-1 dephosphorylation regulates CCL5 expression during monocyte differentiation.Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1 TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)Overcoming resistance to Sonic Hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation.Status of epigenetic chromatin modification enzymes and esophageal squamous cell carcinoma risk in northeast Indian population.Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells.Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism.Inherited and acquired alterations in development of breast cancer.Targeted therapy for breast cancer prevention.Radiation-induced gene signature predicts pathologic complete response to neoadjuvant chemotherapy in breast cancer patients Insulin activates RSK (p90 ribosomal S6 kinase) to trigger a new negative feedback loop that regulates insulin signaling for glucose metabolism.YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.YB-1: oncoprotein, prognostic marker and therapeutic target?YB-1 protein: functions and regulation.Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium.Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinase Y-box-binding protein 1 contributes to IL-7-mediated survival signaling in B-cell precursor acute lymphoblastic leukemia.Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer.Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer.Antitumor effects of BI-D1870 on human oral squamous cell carcinoma.RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts.

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P2860

Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells

http://www.wikidata.org/entity/Q37131331

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Y-box binding protein-1 serine ...... basal-like breast cancer cells

@en

Y-box binding protein-1 serine ...... asal-like breast cancer cells.

@nl

type

label

Y-box binding protein-1 serine ...... basal-like breast cancer cells

@en

Y-box binding protein-1 serine ...... asal-like breast cancer cells.

@nl

prefLabel

Y-box binding protein-1 serine ...... basal-like breast cancer cells

@en

Y-box binding protein-1 serine ...... asal-like breast cancer cells.

@nl

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Breast Cancer Research

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Y-box binding protein-1 serine ...... basal-like breast cancer cells

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P2093

Alastair H Davies

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Anna L Stratford

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Christopher J Fry

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Curtis Desilets

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Isabelle M Berquin

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Sandra E Dunn

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Yong Y Cho

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Yvonne Li

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Zigang Dong

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P2860

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology

RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer

pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

Full length cDNA sequence encoding a nuclease-sensitive element DNA binding protein

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

The selectivity of protein kinase inhibitors: a further update

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R99

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scholarly article

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10.1186/BCR2202

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6

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10

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Philippe P. Roux

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2008-11-27T00:00:00Z

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23499970

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1010998788

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19036157

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2656895

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