Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD
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Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancerPotential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells.Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanomaThe ins and outs of selective kinase inhibitor development.LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies.Targeting the pro-angiogenic forms of VEGF or inhibiting their expression as anti-cancer strategies.Hallmarks of alternative splicing in cancer.Alternative Splicing in CKD.Redirecting SR Protein Nuclear Trafficking through an Allosteric Platform.Pharmacology of Modulators of Alternative Splicing.Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.An in vitro approach to investigate ocular metabolism of a topical, selective β1-adrenergic blocking agent, betaxolol.The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain.Modulators of alternative splicing as novel therapeutics in cancer.Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer.Differential Expression of VEGF-Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis.SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform.Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype.Targeting Splicing in Prostate Cancer.RBPs Play Important Roles in Vascular Endothelial Dysfunction Under Diabetic Conditions
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Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Topical antiangiogenic SRPK1 i ...... rodent models of exudative AMD
@en
Topical antiangiogenic SRPK1 i ...... odent models of exudative AMD.
@nl
type
label
Topical antiangiogenic SRPK1 i ...... rodent models of exudative AMD
@en
Topical antiangiogenic SRPK1 i ...... odent models of exudative AMD.
@nl
prefLabel
Topical antiangiogenic SRPK1 i ...... rodent models of exudative AMD
@en
Topical antiangiogenic SRPK1 i ...... odent models of exudative AMD.
@nl
P2093
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P1476
Topical antiangiogenic SRPK1 i ...... rodent models of exudative AMD
@en
P2093
Andrew D Dick
Chunyun Du
Claire Hopkins
David Ivison
Jules C Hancox
Masatoshi Hagiwara
Melissa V Gammons
Steven J Harper
Tamsyn Clark
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P304
P356
10.1167/IOVS.13-12422
P407
P577
2013-09-05T00:00:00Z