Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation.
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Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fatesIbrutinib in mantle cell lymphoma patients: glass half full? Evidence and opinionHemophagocytic syndrome in children and adultsSH2-dependent autophosphorylation within the Tec family kinase Itk.Autoimmune and other cytopenias in primary immunodeficiencies: pathomechanisms, novel differential diagnoses, and treatmentSLAM-family receptors: immune regulators with or without SAP-family adaptors.Invariant NKT cell response to dengue virus infection in human.Hemophagocytic Syndrome and Critical Illness: New Insights into Diagnosis and Management.T-cell signaling regulated by the Tec family kinase, Itk.Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseasesInterleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.IL-2-inducible T-cell kinase deficiency: clinical presentation and therapeutic approach.Immunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling.T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cellsInhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection.X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia disease: a combined immune deficiency with magnesium defect.Immunologic difference between hypersensitivity to mosquito bite and hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infectionItk: the rheostat of the T cell response.Severe viral infections and primary immunodeficiencies.Host genetics of Epstein-Barr virus infection, latency and disease.CD1d Expression and Invariant NKT Cell Responses in Herpesvirus InfectionsCD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremiaDynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases.Utility of next generation sequencing in clinical primary immunodeficiencies.Recent insights into the pathobiology of innate immune deficienciesDiffuse large B-cell lymphoma in an adolescent female presenting with Epstein-Barr virus-driven hemophagocytic lymphohistiocytosis: a case report.Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis.Simulation of the dynamics of primary immunodeficiencies in CD4+ T-cells.Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis.Hiding lipid presentation: viral interference with CD1d-restricted invariant natural killer T (iNKT) cell activationPartial defects of T-cell development associated with poor T-cell function.Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27.Comparison of Th1/Th2 cytokine profiles between primary and secondary haemophagocytic lymphohistiocytosis.The genetic basis of severe combined immunodeficiency and its variants.Prediction of candidate primary immunodeficiency disease genes using a support vector machine learning approach.Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases.Natural killer cell deficiency.ITK inhibitors in inflammation and immune-mediated disorders.NKT cells: friend or foe during viral infections?
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Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Girls homozygous for an IL-2-i ...... sociated lymphoproliferation.
@en
Girls homozygous for an IL-2-i ...... sociated lymphoproliferation.
@nl
type
label
Girls homozygous for an IL-2-i ...... sociated lymphoproliferation.
@en
Girls homozygous for an IL-2-i ...... sociated lymphoproliferation.
@nl
prefLabel
Girls homozygous for an IL-2-i ...... sociated lymphoproliferation.
@en
Girls homozygous for an IL-2-i ...... sociated lymphoproliferation.
@nl
P2093
P2860
P356
P1476
Girls homozygous for an IL-2-i ...... sociated lymphoproliferation.
@en
P2093
Arndt Borkhardt
Franz Rüschendorf
Hans-Heinrich Wacker
Hans-Jürgen Laws
Hassan Jumaa
Kirsten Huck
Norbert Hübner
Oliver Feyen
Tanja Telieps
Tim Niehues
P2860
P304
P356
10.1172/JCI37901
P407
P577
2009-05-01T00:00:00Z