Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.

Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.

Item
http://www.wikidata.org/entity/Q37192078
A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.Regulation of rDNA transcription by proto-oncogene PELP1Cyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1Role of senescence and mitotic catastrophe in cancer therapy.Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis.Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.miR-150 inhibits terminal erythroid proliferation and differentiation.Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis.Cell cycle proteins as promising targets in cancer therapyA CDK2 activity signature predicts outcome in CDK2-low cancers.In vitro growth inhibition of human cancer cells by novel honokiol analogs.Alteronol inhibits proliferation in HeLa cells through inducing a G1-phase arrest.Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells.
P2860

Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.

Item
http://www.wikidata.org/entity/Q37192078
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
@en
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
@nl
type
label
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
@en
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
@nl
prefLabel
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
@en
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932