Heparanase augments epidermal growth factor receptor phosphorylation: correlation with head and neck tumor progression. - Wikidata - awgldk - TriplyDB

Heparanase augments epidermal growth factor receptor phosphorylation: correlation with head and neck tumor progression.

Heparanase augments epidermal growth factor receptor phosphorylation: correlation with head and neck tumor progression.

http://www.wikidata.org/entity/Q37194268

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Damage-Associated Molecular Patterns in the Course of Lung Cancer--A Review Mechanisms of heparanase inhibitors in cancer therapy.An artificial miRNA against HPSE suppresses melanoma invasion properties, correlating with a down-regulation of chemokines and MAPK phosphorylation.Heparanase promotes engraftment and prevents graft versus host disease in stem cell transplantation Expression of heparanase in soft tissue sarcomas of adults.A novel human heparanase splice variant, T5, endowed with protumorigenic characteristics.Versatile role of heparanase in inflammation Unraveling the specificity of heparanase utilizing synthetic substrates.Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis.Epidermal growth factor-induced heparanase nucleolar localization augments DNA topoisomerase I activity in brain metastatic breast cancer.Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells.Chemical Tumor Biology of Heparan Sulfate Proteoglycans.Heparanase cooperates with Ras to drive breast and skin tumorigenesis Tumorigenic and adhesive properties of heparanase.Heparanase enhances myeloma progression via CXCL10 downregulation.Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis.Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and α-actinin.Allele loss and down-regulation of heparanase gene are associated with the progression and poor prognosis of hepatocellular carcinoma.Prognostic value of heparanase expression and cellular localization in oral cancer.Clinical significance of heparanase splice variant (t5) in renal cell carcinoma: evaluation by a novel t5-specific monoclonal antibody Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.MicroRNA-1258 suppresses breast cancer brain metastasis by targeting heparanase.Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer Post-transcriptional regulation of heparanase gene expression by a 3' AU-rich element Microvessel density and heparanase over-expression in clear cell renal cell cancer: correlations and prognostic significances Heparanase induces signal transducer and activator of transcription (STAT) protein phosphorylation: preclinical and clinical significance in head and neck cancer Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression.The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes Characterization of heparanase-induced phosphatidylinositol 3-kinase-AKT activation and its integrin dependence Heparanase 2 Attenuates Head and Neck Tumor Vascularity and Growth.Heparanase: busy at the cell surface.The identification and characterization of breast cancer CTCs competent for brain metastasis.Heparanase interacts with resistin and augments its activity.Heparanase in inflammation and inflammation-associated cancer.Induction of heparanase-1 expression by mutant B-Raf kinase: role of GA binding protein in heparanase-1 promoter activation.The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy.Berberine inhibits the migration and invasion of T24 bladder cancer cells via reducing the expression of heparanase.

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Heparanase augments epidermal growth factor receptor phosphorylation: correlation with head and neck tumor progression.

http://www.wikidata.org/entity/Q37194268

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Heparanase augments epidermal ...... ad and neck tumor progression.

@en

Heparanase augments epidermal ...... ad and neck tumor progression.

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type

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Heparanase augments epidermal ...... ad and neck tumor progression.

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Heparanase augments epidermal ...... ad and neck tumor progression.

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prefLabel

Heparanase augments epidermal ...... ad and neck tumor progression.

@en

Heparanase augments epidermal ...... ad and neck tumor progression.

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0008-5472.CAN-08-2910

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Cancer Research

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Heparanase augments epidermal ...... ad and neck tumor progression.

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Ilana Doweck

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Inna Naroditsky

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Israel Vlodavsky

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Neta Ilan

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Victoria Cohen-Kaplan

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P2860

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans

Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

Heparanase mediates cell adhesion independent of its enzymatic activity

Heterodimer formation is essential for heparanase enzymatic activity

Heparanase induces endothelial cell migration via protein kinase B/Akt activation

Processing and activation of latent heparanase occurs in lysosomes

Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate

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10077-10085

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scholarly article

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10.1158/0008-5472.CAN-08-2910

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24

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68

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2008-12-01T00:00:00Z

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19074873

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phosphorylation

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2682916

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