Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
about
Sulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanaseInvolvement of heparanase in atherosclerosis and other vessel wall pathologiesM402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasisExpression of heparanase in soft tissue sarcomas of adults.Combination therapy with low molecular weight heparin and Adriamycin results in decreased breast cancer cell metastasis in C3H mice.Heparanase enhances myeloma progression via CXCL10 downregulation.SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis.Heparanase induces signal transducer and activator of transcription (STAT) protein phosphorylation: preclinical and clinical significance in head and neck cancerSignificance of heparanase in cancer and inflammation.The potential of heparanase as a therapeutic target in cancerMacrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression.Impact of heparanase and the tumor microenvironment on cancer metastasis and angiogenesis: basic aspects and clinical applicationsHeparanase-induced shedding of syndecan-1/CD138 in myeloma and endothelial cells activates VEGFR2 and an invasive phenotype: prevention by novel synstatins.Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases.The prognostic significance of heparanase expression in metastatic melanomaCancer-associated lysosomal changes: friends or foes?The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.Heparanase in inflammation and inflammation-associated cancer.The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.Profiling glycol-split heparins by high-performance liquid chromatography/mass spectrometry analysis of their heparinase-generated oligosaccharides.Physiological, Tumor, and Metastatic Niches: Opportunities and Challenges for Targeting the Tumor Microenvironment.Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Diacetyloxyl derivatization of the fibroblast growth factor inhibitor dobesilate enhances its anti-inflammatory, anti-angiogenic and anti-tumoral activities.Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy.Phosphomannopentaose sulfate (PI-88) suppresses angiogenesis by downregulating heparanase and vascular endothelial growth factor in an oxygen-induced retinal neovascularization animal model.Heparanase: From basic research to therapeutic applications in cancer and inflammation.
P2860
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P2860
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@ast
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@en
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@nl
type
label
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@ast
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@en
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@nl
prefLabel
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@ast
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@en
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
@nl
P2093
P2860
P1476
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma
@en
P2093
Claudio Pisano
Franco Zunino
Inna Naroditsky
Isaac Meller
Israel Vlodavsky
Itay Shafat
Josephine Issakov
Monica Tortoreto
Myriam Weyl Ben-Arush
P2860
P304
P356
10.1111/J.1582-4934.2010.01190.X
P577
2011-09-01T00:00:00Z