Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration - Wikidata - awgldk - TriplyDB

Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

http://www.wikidata.org/entity/Q37241319

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Redox biology in pulmonary arterial hypertension (2013 Grover Conference Series)Role of caveolin-1 and caveolae signaling in endotoxemia and sepsis The genetics of pulmonary arterial hypertension Reactive nitrogen species in cellular signaling Formation of vascular S-nitrosothiols and plasma nitrates/nitrites following inhalation of diesel emissions A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung Therapeutic Benefits of Induced Pluripotent Stem Cells in Monocrotaline-Induced Pulmonary Arterial Hypertension Regulation of cellular communication by signaling microdomains in the blood vessel wall.Spontaneous lung dysfunction and fibrosis in mice lacking connexin 40 and endothelial cell connexin 43 Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability.Dependence of Golgi apparatus integrity on nitric oxide in vascular cells: implications in pulmonary arterial hypertension.Pulmonary arterial hypertension: the clinical syndrome.Sex differences in the pulmonary circulation: implications for pulmonary hypertension Aberrant caveolin-1-mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension.A novel insight into the mechanism of pulmonary hypertension involving caveolin-1 deficiency and endothelial nitric oxide synthase activation Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation.Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine.Heritable forms of pulmonary arterial hypertension.New trial designs and potential therapies for pulmonary artery hypertension.SOD and inhaled nitric oxide normalize phosphodiesterase 5 expression and activity in neonatal lambs with persistent pulmonary hypertension.Nitroglycerin tolerance in caveolin-1 deficient mice.Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression.Biomechanical properties and innervation of the female caveolin-1-deficient detrusor.Protein tyrosine nitration in cellular signal transduction pathways.New perspectives for the treatment of pulmonary hypertension Common and rare genetic risk factors for glaucoma.Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension.Cell-specific dual role of caveolin-1 in pulmonary hypertension.Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF.A noninhibitory mutant of the caveolin-1 scaffolding domain enhances eNOS-derived NO synthesis and vasodilation in mice.PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins.Human immunodeficiency virus transgenic rats exhibit pulmonary hypertension Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism Protein trafficking dysfunctions: Role in the pathogenesis of pulmonary arterial hypertension.Abnormal expression of NSF, α-SNAP and SNAP23 in pulmonary arterial hypertension in rats treated with monocrotaline.Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA Overexpression of cationic amino acid transporter-1 increases nitric oxide production in hypoxic human pulmonary microvascular endothelial cells N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase.Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice.

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Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

http://www.wikidata.org/entity/Q37241319

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on July 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Persistent eNOS activation sec ...... d humans through PKG nitration

@en

Persistent eNOS activation sec ...... humans through PKG nitration.

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type

label

Persistent eNOS activation sec ...... d humans through PKG nitration

@en

Persistent eNOS activation sec ...... humans through PKG nitration.

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prefLabel

Persistent eNOS activation sec ...... d humans through PKG nitration

@en

Persistent eNOS activation sec ...... humans through PKG nitration.

@nl

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Journal of Clinical Investigation

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Persistent eNOS activation sec ...... d humans through PKG nitration

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Asrar B Malik

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Hari-Hara S K Potula

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Jason X-J Yuan

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John Wharton

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Julia H Huang

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Muhammad K Mirza

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Steven M Vogel

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Viktor Brovkovych

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Yidan D Zhao

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You-Yang Zhao

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P2860

S-nitrosothiols signal hypoxia-mimetic vascular pathology

Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis

Protective role of endothelial nitric oxide synthase

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice

Protein S-nitrosylation: purview and parameters

Caveolin, a protein component of caveolae membrane coats

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2009-2018

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scholarly article

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10.1172/JCI33338

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2009-07-01T00:00:00Z

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19487814

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arterial hypertension

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2701851

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