Hydrogen peroxide-mediated neuronal cell death induced by an endogenous neurotoxin, 3-hydroxykynurenine.
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Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylaseCloning and functional expression of human kynurenine 3-monooxygenaseCurrent Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple SclerosisInflammation Models of Depression in Rodents: Relevance to Psychotropic Drug DiscoveryKynurenine 3-Monooxygenase: An Influential Mediator of NeuropathologyThe Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and AutoimmunityStructural basis of kynurenine 3-monooxygenase inhibitionChanging the face of kynurenines and neurotoxicity: therapeutic considerationsAntioxidant Properties of Kynurenines: Density Functional Theory CalculationsTryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolitesInterference of some tryptophan metabolites in the formation of melanin in vitro.The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction3-Hydroxykynurenine transaminase identity with alanine glyoxylate transaminase. A probable detoxification protein in Aedes aegypti.Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterization and protection by dantrolene and Bcl-2 overexpression.Neurotoxic and neuroprotective metabolites of kynurenine in patients with renal cell carcinoma treated with interferon-alpha: course and relationship with psychiatric status.Kynurenine Pathway Activation in Human African TrypanosomiasisWidespread sulfenic acid formation in tissues in response to hydrogen peroxide.Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced Hypotension?Redox reactions related to indoleamine 2,3-dioxygenase and tryptophan metabolism along the kynurenine pathway.Tryptophan metabolites and brain disorders.The metabolic profile of long-lived Drosophila melanogasterKynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2,3-dioxygenase.Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminaseInduction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: apoptosis through the formation of 3-hydroxykynurenine.Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-D-aspartate neurotoxicity.Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder.Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1.Impaired kynurenine pathway metabolism in the prefrontal cortex of individuals with schizophrenia.Cytomegalovirus Antibody Elevation in Bipolar Disorder: Relation to Elevated Mood StatesKynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice.Apicomplexan parasite, Eimeria falciformis, co-opts host tryptophan catabolism for life cycle progression in mouseThe tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesisNMR-based metabolomics of urine in a mouse model of Alzheimer's disease: identification of oxidative stress biomarkers.Biochemical and phenotypic abnormalities in kynurenine aminotransferase II-deficient miceTryptophan-kynurenine pathway is dysregulated in inflammation, and immune activation.Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington's disease.Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease.
P2860
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P2860
Hydrogen peroxide-mediated neuronal cell death induced by an endogenous neurotoxin, 3-hydroxykynurenine.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Hydrogen peroxide-mediated neu ...... urotoxin, 3-hydroxykynurenine.
@en
Hydrogen peroxide-mediated neu ...... urotoxin, 3-hydroxykynurenine.
@nl
type
label
Hydrogen peroxide-mediated neu ...... urotoxin, 3-hydroxykynurenine.
@en
Hydrogen peroxide-mediated neu ...... urotoxin, 3-hydroxykynurenine.
@nl
prefLabel
Hydrogen peroxide-mediated neu ...... urotoxin, 3-hydroxykynurenine.
@en
Hydrogen peroxide-mediated neu ...... urotoxin, 3-hydroxykynurenine.
@nl
P2093
P2860
P356
P1476
Hydrogen peroxide-mediated neu ...... urotoxin, 3-hydroxykynurenine.
@en
P2093
P2860
P304
12553-12558
P356
10.1073/PNAS.93.22.12553
P407
P577
1996-10-01T00:00:00Z