Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation. - Wikidata - awgldk - TriplyDB

Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation.

Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation.

http://www.wikidata.org/entity/Q37252338

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Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61 Protein phosphatases and Alzheimer's disease Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice.Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease Checking the STEP-Associated Trafficking and Internalization of Glutamate Receptors for Reduced Cognitive Deficits: A Machine Learning Approach-Based Cheminformatics Study and Its Application for Drug Repurposing In vivo axonal transport deficits in a mouse model of fronto-temporal dementia.Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.What is the new target inhibiting the progression of Alzheimer's disease Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders.Protein tyrosine phosphatases as potential therapeutic targets.Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway Activation of extracellular signal-regulated kinase signaling in the pedunculopontine tegmental cells is involved in the maintenance of sleep in rats.STEP regulation of seizure thresholds in the hippocampus.Striatal-enriched protein tyrosine phosphatase (STEP) knockout mice have enhanced hippocampal memory.Calcium/calmodulin kinase II in the pedunculopontine tegmental nucleus modulates the initiation and maintenance of wakefulness Spatially distinct actions of metabotropic glutamate receptor activation in dorsal lateral geniculate nucleus STEP signaling pathway mediates psychomotor stimulation and morphine withdrawal symptoms, but not for reward, analgesia and tolerance Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.Zn2+-dependent Activation of the Trk Signaling Pathway Induces Phosphorylation of the Brain-enriched Tyrosine Phosphatase STEP: MOLECULAR BASIS FOR ZN2+-INDUCED ERK MAPK ACTIVATION.Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels.Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition Seizure-Induced Regulations of Amyloid-β, STEP61, and STEP61 Substrates Involved in Hippocampal Synaptic Plasticity.The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity.STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit.Taking STEPs forward to understand fragile X syndrome.Physiological signaling specificity by protein tyrosine phosphatases.Molecular mechanism of ERK dephosphorylation by striatal-enriched protein tyrosine phosphatase.A STEP forward in neural function and degeneration.Synaptic integration by different dendritic compartments of hippocampal CA1 and CA2 pyramidal neurons.

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P2860

Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation.

http://www.wikidata.org/entity/Q37252338

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on January 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Knockout of striatal enriched ...... reased ERK1/2 phosphorylation.

@en

Knockout of striatal enriched ...... reased ERK1/2 phosphorylation.

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type

label

Knockout of striatal enriched ...... reased ERK1/2 phosphorylation.

@en

Knockout of striatal enriched ...... reased ERK1/2 phosphorylation.

@nl

prefLabel

Knockout of striatal enriched ...... reased ERK1/2 phosphorylation.

@en

Knockout of striatal enriched ...... reased ERK1/2 phosphorylation.

@nl

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Knockout of striatal enriched ...... reased ERK1/2 phosphorylation.

@en

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Deepa V Venkitaramani

http://www.w3.org/2001/XMLSchema#string

Li Ding

http://www.w3.org/2001/XMLSchema#string

Lyal Tressler

http://www.w3.org/2001/XMLSchema#string

Melanie Allen

http://www.w3.org/2001/XMLSchema#string

Paul J Lombroso

http://www.w3.org/2001/XMLSchema#string

Pradeep Kurup

http://www.w3.org/2001/XMLSchema#string

Rosalba Sacca

http://www.w3.org/2001/XMLSchema#string

Surojit Paul

http://www.w3.org/2001/XMLSchema#string

Yongfang Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum

A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures

STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum

Regulation of NMDA receptor trafficking by amyloid-beta

NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling

Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation

Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking

Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase

The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala

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69-81

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scholarly article

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10.1002/SYN.20608

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1

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63

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Marina R Picciotto

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2009-01-01T00:00:00Z

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23395700

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18932218

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corpus striatum

phosphorylation

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2706508

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