Mechanisms of beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle: insights from experimental and model-based analysis
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Comprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependencePrediction of Thorough QT study results using action potential simulations based on ion channel screensComputational modeling of inhibition of voltage-gated Ca channels: identification of different effects on uterine and cardiac action potentials.Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient.A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis.Role of action potential configuration and the contribution of C²⁺a and K⁺ currents to isoprenaline-induced changes in canine ventricular cells.An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation.β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle.Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains.
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P2860
Mechanisms of beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle: insights from experimental and model-based analysis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mechanisms of beta-adrenergic modulation of I
@nl
Mechanisms of beta-adrenergic ...... ental and model-based analysis
@en
type
label
Mechanisms of beta-adrenergic modulation of I
@nl
Mechanisms of beta-adrenergic ...... ental and model-based analysis
@en
prefLabel
Mechanisms of beta-adrenergic modulation of I
@nl
Mechanisms of beta-adrenergic ...... ental and model-based analysis
@en
P2093
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P1433
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Mechanisms of beta-adrenergic ...... ental and model-based analysis
@en
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Cristiana Corsi
Marcella Rocchetti
Stefano Severi
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P304
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10.1016/J.BPJ.2009.02.017
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P50
P577
2009-05-01T00:00:00Z