Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection
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Photoreceptors in diabetic retinopathyA missense mutation in HK1 leads to autosomal dominant retinitis pigmentosa.Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.The p110α isoform of phosphoinositide 3-kinase is essential for cone photoreceptor survival.The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina.Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment.Glucose, lactate, and shuttling of metabolites in vertebrate retinasPHLPP phosphatases as a therapeutic target in insulin resistance-related diseases.Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability.Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin.Glaucoma pathogenesis and neurotrophins: Focus on the Molecular and Genetic basis for Therapeutic prospects.Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa.Regulation of Brain-Derived Neurotrophic Factor and Growth Factor Signaling Pathways by Tyrosine Phosphatase Shp2 in the Retina: A Brief Review.Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa.
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Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 30 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Light activation of the insuli ...... ism of retinal neuroprotection
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Light activation of the insuli ...... sm of retinal neuroprotection.
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type
label
Light activation of the insuli ...... ism of retinal neuroprotection
@en
Light activation of the insuli ...... sm of retinal neuroprotection.
@nl
prefLabel
Light activation of the insuli ...... ism of retinal neuroprotection
@en
Light activation of the insuli ...... sm of retinal neuroprotection.
@nl
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Light activation of the insuli ...... ism of retinal neuroprotection
@en
P2093
Ammaji Rajala
Raju V S Rajala
Robert E Anderson
Vivek K Gupta
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P304
P356
10.1016/J.MITO.2013.08.005
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2013-08-30T00:00:00Z