Recent highlights in antimalarial drug resistance and chemotherapy research.
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Occurrence of pfatpase6 Single Nucleotide Polymorphisms Associated with Artemisinin Resistance among Field Isolates of Plasmodium falciparum in North-Eastern TanzaniaThat Was Then But This Is Now: Malaria Research in the Time of an Eradication AgendaPurified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to ArtemisininsArtemisinin-based combination therapies: a vital tool in efforts to eliminate malariaLipoic acid metabolism of Plasmodium--a suitable drug targetRedox-dependent lipoylation of mitochondrial proteins in Plasmodium falciparumIn vitro and in vivo activities of 1-hydroxy-2-alkyl-4(1H)quinolone derivatives against Toxoplasma gondii.Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum.Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.Artemisinin Antimalarials: Preserving the "Magic Bullet"Reduced polymorphism in the Kelch propeller domain in Plasmodium vivax isolates from Cambodia.Discovery, mechanisms of action and combination therapy of artemisininProbing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparumUnderstanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors.Polymorphism in PfMRP1 (Plasmodium falciparum multidrug resistance protein 1) amino acid 1466 associated with resistance to sulfadoxine-pyrimethamine treatment.Cytoadherence of erythrocytes invaded by Plasmodium falciparum: quantitative contact-probing of a human malaria receptor.Plasmodium falciparum: new molecular targets with potential for antimalarial drug development.Identification of Compounds with Efficacy against Malaria Parasites from Common North American Plants.Exploring the Molecular Basis of Qo bc1 Complex Inhibitors Activity to Find Novel Antimalarials Hits.Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.Attenuation of endoplasmic reticulum stress in Pelizaeus-Merzbacher disease by an anti-malaria drug, chloroquine.A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.Plasmodium falciparum ATP6 not under selection during introduction of artemisinin combination therapy in Peru.Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production.A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species.Crystal structure of lipoate-bound lipoate ligase 1, LipL1, from Plasmodium falciparum.Inferred relatedness and heritability in malaria parasites.Repurposing drugs to target the malaria parasite unfolding protein response.Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strainsStructure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-dihydropteroate synthase from Plasmodium vivax sheds light on drug resistance
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Recent highlights in antimalarial drug resistance and chemotherapy research.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Recent highlights in antimalarial drug resistance and chemotherapy research.
@en
Recent highlights in antimalarial drug resistance and chemotherapy research.
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type
label
Recent highlights in antimalarial drug resistance and chemotherapy research.
@en
Recent highlights in antimalarial drug resistance and chemotherapy research.
@nl
prefLabel
Recent highlights in antimalarial drug resistance and chemotherapy research.
@en
Recent highlights in antimalarial drug resistance and chemotherapy research.
@nl
P2860
P356
P1476
Recent highlights in antimalarial drug resistance and chemotherapy research.
@en
P2093
Richard T Eastman
Stephen A Ward
P2860
P304
P356
10.1016/J.PT.2008.09.005
P577
2008-10-18T00:00:00Z