An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
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Chronic neutrophilic leukemia 2014: Update on diagnosis, molecular genetics, and managementOncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CMLInherited biallelic CSF3R mutations in severe congenital neutropenia.CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia.Chronic idiopathic neutrophilia in two twins.Genome-wide association study for posthitis in the free-living population of European bison (Bison bonasus)Mutations in the transmembrane and juxtamembrane domains enhance IL27R transforming activityThe Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.Animal models of human granulocyte diseases.An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms.What's different about atypical CML and chronic neutrophilic leukemia?Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy.Chronic neutrophilic leukemia 2016: Update on diagnosis, molecular genetics, prognosis, and management.Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies.Genomics of chronic neutrophilic leukemia.Advances in understanding the pathogenesis of familial myeloproliferative neoplasms.Recent Progress in Chronic Neutrophilic Leukemia and Atypical Chronic Myeloid Leukemia.Prevalence of a new auto-activating colony stimulating factor 3 receptor mutation (CSF3R-T595I) in acute myeloid leukemia and severe congenital neutropenia.JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders.Chronic neutrophilic leukemia: new science and new diagnostic criteria.Mutation of the colony-stimulating factor-3 receptor gene is a rare event with poor prognosis in chronic myelomonocytic leukemia.Granulocyte colony-stimulating factor receptor T595I (T618I) mutation confers ligand independence and enhanced signaling.Identification of novel MECOM gene fusion and personalized therapeutic targets through integrative clinical sequencing in secondary acute myeloid leukemia in a patient with severe congenital neutropenia: a case report and literature review.Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation.Colony-stimulating factor-3 receptor, watch out for polymorphisms.
P2860
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P2860
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 July 2009
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
@en
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
@nl
type
label
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
@en
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
@nl
prefLabel
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
@en
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
@nl
P2093
P2860
P50
P356
P1476
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
@en
P2093
Jean-Michel Boulet
Jean-Pierre Le Couédic
Mayuka Nakatake
Miki Itaya
Najet Debili
Steven O Smith
William Vainchenker
Yanyan Zhang
P2860
P304
P356
10.1084/JEM.20090693
P407
P577
2009-07-20T00:00:00Z