Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
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Generation of amyloid-β is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrinProtein phosphatase 5 protects neurons against amyloid-beta toxicityAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseMolecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain TissueMolecular Basis of Substrate Recognition and Degradation by Human Presequence ProteaseAlzheimer's disease and prion proteinAnimal models for Alzheimer's disease and frontotemporal dementia: a perspectiveATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicityPreparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and functionDi-Huang-Yi-Zhi herbal formula attenuates amyloid-β-induced neurotoxicity in PC12 cells.Influence of the stability of a fused protein and its distance to the amyloidogenic segment on fibril formation.Calcium signaling and amyloid toxicity in Alzheimer disease.Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: implications for human motor neuron disease.S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors.Role of microglia adenosine A(2A) receptors in retinal and brain neurodegenerative diseases.Cholesterol increases ventricular volume in a rabbit model of Alzheimer's disease.Targeting S100B in Cerebral Ischemia and in Alzheimer's Disease.Fibril elongation by Aβ(17-42): kinetic network analysis of hybrid-resolution molecular dynamics simulationsGanglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain.Mechanism of fiber assembly: treatment of Aβ peptide aggregation with a coarse-grained united-residue force field.Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse modelαB-Crystallin inhibits the cell toxicity associated with amyloid fibril formation by κ-casein and the amyloid-β peptide.Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation.Reduction of β-amyloid deposits by γ-secretase inhibitor is associated with the attenuation of secondary damage in the ipsilateral thalamus and sensory functional improvement after focal cortical infarction in hypertensive rats.Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesionEffect of alanine replacement of l17 and f19 on the aggregation and neurotoxicity of arctic-type aβ40Actions of β-amyloid protein on human neurons are expressed through the amylin receptor.Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantationAmyloid beta-protein assembly and Alzheimer disease.APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent.CLOCK Genes and Circadian Rhythmicity in Alzheimer Disease.Changes in brain β-amyloid deposition and aquaporin 4 levels in response to altered agrin expression in miceStem cell factor and granulocyte colony-stimulating factor reduce β-amyloid deposits in the brains of APP/PS1 transgenic miceAmyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation.Truncated Amyloid-β(11-40/42) from Alzheimer Disease Binds Cu2+ with a Femtomolar Affinity and Influences Fiber Assembly.Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysinQuantitative proteomic analysis of amniocytes reveals potentially dysregulated molecular networks in Down syndrome.Oxidative stress and the pathogenesis of Alzheimer's disease.
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Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
@en
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
@nl
type
label
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
@en
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
@nl
prefLabel
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
@en
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
@nl
P2860
P356
P1476
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease.
@en
P2093
Bruce A Yankner
P2860
P304
P356
10.1074/JBC.R800018200
P407
P577
2008-10-28T00:00:00Z