AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells - Wikidata - awgldk - TriplyDB

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

http://www.wikidata.org/entity/Q37348251

about

Self-complementary AAVs induce more potent transgene product-specific immune responses compared to a single-stranded genome The emerging role of viral vectors as vehicles for DMD gene editing Adeno-associated Virus as a Mammalian DNA Vector Progress and prospects: immune responses to viral vectors Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping Characterization of genome integrity for oversized recombinant AAV vector.AAV's anatomy: roadmap for optimizing vectors for translational success Strategies to modulate immune responses: a new frontier for gene therapy Immune responses to AAV in canine muscle monitored by cellular assays and noninvasive imaging.Influence of immune responses in gene/stem cell therapies for muscular dystrophies.Comparison of adeno-associated virus pseudotype 1, 2, and 8 vectors administered by intramuscular injection in the treatment of murine phenylketonuria Stem cell transplantation for muscular dystrophy: the challenge of immune response.The potential of adeno-associated viral vectors for gene delivery to muscle tissue.Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions.Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial.Adeno-associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them.Progress and prospects of gene therapy clinical trials for the muscular dystrophies.In vitro and In vivo Model Systems for Hemophilia A Gene Therapy.Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.Adeno-associated virus vectors serotype 2 induce prolonged proliferation of capsid-specific CD8+ T cells in mice.State-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications.Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats.Rescuing the failing heart by targeted gene transfer Capsid-expressing DNA in AAV vectors and its elimination by use of an oversize capsid gene for vector production.Therapeutic approaches to muscular dystrophy.A barrel of monkeys: scAAV8 gene therapy for hemophilia in nonhuman primates.Adeno-associated viral vector serotype 5 poorly transduces liver in rat models Reproducible high yields of recombinant adeno-associated virus produced using invertebrate cells in 0.02- to 200-liter cultures.Immune Responses to rAAV6: The Influence of Canine Parvovirus Vaccination and Neonatal Administration of Viral Vector A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8.Capsid-specific T-cell responses to natural infections with adeno-associated viruses in humans differ from those of nonhuman primates Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors Adenovirus-associated virus vector-mediated gene transfer in hemophilia B Intravenous AAV8 Encoding Urocortin-2 Increases Function of the Failing Heart in Mice.Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer.Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies

P2860

Q24625426-A992C43F-6B09-4E65-BD81-6B712FF66B78 Q26746647-DC72366D-6279-471C-9472-8409E43BE164 Q26782605-92EFF428-1932-4EE5-AB17-E798D743937A Q28264531-A5E22F21-A24F-4D2B-B6D7-8207F393EB8B Q28389778-F4497DED-B4FC-4A61-8988-72C0845C70E7 Q30514014-CD80B413-A65B-4E86-848B-CD1046027E24 Q33576852-F777E5A7-4B7F-4C33-BAFD-9DF142597A55 Q33659389-D498C12B-89C4-40D5-9B6D-5966A43986EA Q33713999-5209B26E-458C-43E1-8C70-C783FE0F35A8 Q33731159-CF72B603-6881-4C3A-8F83-73829B64CCE0 Q33736192-E1D9795F-EEFC-44DD-8C9D-AE1A8CD24B14 Q33832790-D5187069-E496-46A8-A4AE-E7D2CC0A185E Q33902416-0E558B0E-C41B-4F2B-8495-76DB0E121B6D Q33902499-6A077D4F-9CC4-4AFC-89F6-01B5EE5B9C12 Q33931862-856F0944-F8C2-4D49-8182-BB36BA0A53A3 Q33938435-17A9697D-A09D-4D25-91B6-0DBA94453867 Q34025098-A3BE79F8-410C-4E90-A3AE-302217455FD2 Q34311144-4534721A-1340-4BB2-9B88-191226791A5E Q34370111-D68454E7-34FC-42CA-B171-DA29119A7537 Q34497471-2B0A82DA-E560-477B-97E5-51BBCF2397DA Q34499850-E1BFF63F-C44D-42EA-8CF4-AA2DD1622618 Q34535446-7056FFBF-BE6F-468F-B3E1-C8A3E552C0E4 Q34621723-70EE9E1B-5B51-4AC9-B033-764389C10852 Q34664690-E2309FFA-5C82-4202-82A2-72BE26C40C2A Q34684229-756A1DAE-06FB-410C-9512-F4EF1B25EEB2 Q34757960-23B7D46A-EFB7-42BD-BD6B-AAB67903EC3E Q34770593-B3FF77F2-174B-4584-948C-5CBAB58236DF Q34982869-E3D4567A-0579-4B03-BC52-2DA970473761 Q34994549-2686925A-75AD-4536-8635-F41347BCBD69 Q35080025-670B5383-0FB6-4FA7-9416-A7D5226A196F Q35174927-D9D7C051-599C-46C8-9ADA-86080381E923 Q35513407-FA40617C-4176-4BA9-BEDB-5E80977E8776 Q35568505-0B4314D7-2DEA-4239-8362-457097C80EF9 Q35568563-667CE797-A32A-48DE-B770-F8990BDBF235 Q35575706-4AD22C7A-99C9-4E58-8BC2-10C5A5849665 Q35691659-8E5DA1AC-AC8C-44B8-A372-DBB4E8A15AFD Q35821871-7FF1B6CD-7B44-4D94-84BB-A0197AE98AC6 Q35871626-33F85AD9-2A99-4D32-B9CC-620236B33AF9 Q35876970-6DF72FE9-C1AC-4EA7-9E49-3D714DD731DA Q35884548-4E50CE97-0B96-4D30-9B7E-E09E85D1EE41

P2860

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

http://www.wikidata.org/entity/Q37348251

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 08 June 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

AAV-1-mediated gene transfer t ...... ion of capsid-specific T cells

@en

AAV-1-mediated gene transfer t ...... on of capsid-specific T cells.

@nl

type

label

AAV-1-mediated gene transfer t ...... ion of capsid-specific T cells

@en

AAV-1-mediated gene transfer t ...... on of capsid-specific T cells.

@nl

prefLabel

AAV-1-mediated gene transfer t ...... ion of capsid-specific T cells

@en

AAV-1-mediated gene transfer t ...... on of capsid-specific T cells.

@nl

P1433

Q37348251-870A2BBB-1896-4537-AEEB-D944D37BD2BD

P1476

Q37348251-68C66DAB-C7A2-46AF-AB9D-0EB4A8468246

P2093

Q37348251-054BCA57-62C8-46E0-AF99-AB4D27218CCD

Q37348251-091208DD-C5AA-49B0-865B-9F4F9BEF9F9E

Q37348251-22D5C03F-8467-46D4-A815-6AB9B4B9C3EB

Q37348251-40E302C2-45A7-43CC-BB23-98D69C736646

Q37348251-56E58CAD-F87A-430A-85DA-7086F3BF7DB7

Q37348251-65F57365-8AF1-4CA7-A572-0C80D0103DEE

Q37348251-837A8BF4-E892-43EC-88FC-E99ABFCDBF87

Q37348251-BD1CB676-ADF5-4C6A-9D66-94F3E8892CA2

Q37348251-DD2C1E6F-F5AC-43DA-AFCA-E8627B8595BC

Q37348251-E0FF16F5-39F6-4FEC-AD65-3F4F20C5F370

P2860

Q37348251-039AB208-A05D-4095-A9B9-D12835F963E7

Q37348251-1F142EF1-097D-42CD-944C-0C0C51884D90

Q37348251-25B1A0FC-2B51-4F67-A285-122C826B9BFE

Q37348251-2E5E7161-C24F-4E3B-97A4-16E989BE0D69

Q37348251-2F71B5A5-D4F5-4DCD-9D3A-CA78D05BB194

Q37348251-30AAF370-D22E-4572-93FA-3A1A34BFCFA9

Q37348251-310AB1AB-6D85-46AD-83EE-4B41C842EF14

Q37348251-3D0B878B-D33E-44D7-919B-683D668C1FFF

Q37348251-43BE77A7-41C9-4BB8-8F77-AC6708CB2A08

Q37348251-46D54D8E-A94B-4748-9D0B-406B407C317B

P304

Q37348251-24504EB5-B0D6-45A2-B164-E6B94ABC6348

P31

Q37348251-F35FC644-1CAB-47D9-8937-C1CDC7768D06

P356

Q37348251-D0883B41-F585-46B7-A71C-B13129DB4079

P407

Q37348251-D9DD85DA-A56A-40D7-90F0-9BD4E65F612B

P433

Q37348251-2FFF9E4C-135A-4D90-BEF9-3AE10FA9B826

P478

Q37348251-BBE8F011-B29A-4642-9AE0-F0285F89A59F

P577

Q37348251-A3F92264-7647-4B4B-A9E2-E4351AF68A6F

P5875

Q37348251-A4ED5A93-6F83-461F-858B-B20CC4C5960B

P698

Q37348251-FD46343A-F37C-4C6F-B4AF-F2028778DBAF

P932

Q37348251-4CED80AF-4A48-4AB5-8316-0DC9FA4942FA

P356

BLOOD-2008-07-167510

P1433

P1476

AAV-1-mediated gene transfer t ...... ion of capsid-specific T cells

@en

P2093

Daniel J Hui

http://www.w3.org/2001/XMLSchema#string

Erik S Stroes

http://www.w3.org/2001/XMLSchema#string

Etiena Basner-Tschakarjan

http://www.w3.org/2001/XMLSchema#string

Federico Mingozzi

http://www.w3.org/2001/XMLSchema#string

Janneke J Meulenberg

http://www.w3.org/2001/XMLSchema#string

John J Kastelein

http://www.w3.org/2001/XMLSchema#string

Katherine A High

http://www.w3.org/2001/XMLSchema#string

Michael R Betts

http://www.w3.org/2001/XMLSchema#string

Natalie A Hutnick

http://www.w3.org/2001/XMLSchema#string

Nicole C Hasbrouck

http://www.w3.org/2001/XMLSchema#string

P2860

Human parvovirus B19.

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Effect of gene therapy on visual function in Leber's congenital amaurosis

Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Identification of mouse AAV capsid-specific CD8+ T cell epitopes.

Immune responses to adenovirus and adeno-associated virus in humans.

AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer.

P304

2077-2086

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1182/BLOOD-2008-07-167510

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

114

http://www.w3.org/2001/XMLSchema#string

P577

2009-06-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26276011

http://www.w3.org/2001/XMLSchema#string

P698

19506302

http://www.w3.org/2001/XMLSchema#string

P932

2744569

http://www.w3.org/2001/XMLSchema#string