Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide. - Wikidata - awgldk - TriplyDB

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

http://www.wikidata.org/entity/Q36143372

about

Purified human BRCA2 stimulates RAD51-mediated recombination The role of BRCA2 in replication-coupled DNA interstrand cross-link repair in vitro Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51 Homologous recombination in DNA repair and DNA damage tolerance Hed1 regulates Rad51-mediated recombination via a novel mechanism.Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo.Functional attributes of the Saccharomyces cerevisiae meiotic recombinase Dmc1.Molding BRCA2 function through its interacting partners Unraveling the mechanism of BRCA2 in homologous recombination Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks Reconstitution of DNA strand exchange mediated by Rhp51 recombinase and two mediators Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination Direct observation of twisting steps during Rad51 polymerization on DNA.Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions.DNA binding, annealing, and strand exchange activities of Brh2 protein from Ustilago maydis.Molecular anatomy of the recombination mediator function of Saccharomyces cerevisiae Rad52.A novel role of the chromokinesin Kif4A in DNA damage response.Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C.Rad51 inhibits translocation formation by non-conservative homologous recombination in Saccharomyces cerevisiae.Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.Single-molecule imaging brings Rad51 nucleoprotein filaments into focus.Taking a Bad Turn: Compromised DNA Damage Response in Leukemia Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications.Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair.Mechanisms of double-strand break repair in somatic mammalian cells.Arabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responses.Biochemistry of eukaryotic homologous recombination.Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.The budding yeast Mei5-Sae3 complex interacts with Rad51 and preferentially binds a DNA fork structure.Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52 Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement.Real-time measurements of the nucleation, growth and dissociation of single Rad51-DNA nucleoprotein filaments Targeting cancer with a lupus autoantibody

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P2860

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

http://www.wikidata.org/entity/Q36143372

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

@ast

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

@en

type

label

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

@ast

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

@en

prefLabel

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

@ast

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.

@en

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Journal of Biological Chemistry

P1476

Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide

@en

P2093

Joseph San Filippo

http://www.w3.org/2001/XMLSchema#string

Julia Etchin

http://www.w3.org/2001/XMLSchema#string

Michael G Sehorn

http://www.w3.org/2001/XMLSchema#string

Patrick Sung

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P2860

Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage.

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein.

DSS1 is required for the stability of BRCA2

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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10.1074/JBC.M601249200

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2077811

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