Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice. - Wikidata - awgldk - TriplyDB

Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice.

Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice.

http://www.wikidata.org/entity/Q37375570

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Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation What Is Breast in the Bone?Growth hormone receptor is expressed in human breast cancer Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism.Prolactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer Cells The Pit-1/Pou1f1 transcription factor regulates and correlates with prolactin expression in human breast cell lines and tumors The role of prolactin and growth hormone in breast cancer.Effects of growth hormone and prolactin on hematopoiesis.Biological significance of prolactin in gynecologic cancers.Unexploited therapies in breast and prostate cancer: blockade of the prolactin receptor.Whole genome microarray analysis of growth hormone-induced gene expression in bone: T-box3, a novel transcription factor, regulates osteoblast proliferation.Effects of prolactin on hematopoiesis.What can we learn from rodents about prolactin in humans?The role of prolactin in mammary carcinoma.Prolactin potentiates transforming growth factor alpha induction of mammary neoplasia in transgenic mice Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice Coexistence of lactating adenoma and invasive ductal adenocarcinoma of the breast in a pregnant woman The two faces of Janus kinases and their respective STATs in mammary gland development and cancer Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia The basal function of teleost prolactin as a key regulator on ion uptake identified with zebrafish knockout models Prolactin and the prolactin receptor: new targets of an old hormone.Concurrent Lactating Adenoma and Infiltrating Ductal Carcinoma: A Case Report.In vitro effects of recombinant human growth hormone on growth of human gastric cancer cell line BGC823 cells.Autocrine prolactin: an emerging market for homegrown (prolactin) despite the imports.Retinoic acid modulates prolactin receptor expression and prolactin-induced STAT-5 activation in breast cancer cells in vitro.Modeling prolactin actions in breast cancer in vivo: insights from the NRL-PRL mouse.GHR/PRLR Heteromultimer Is Composed of GHR Homodimers and PRLR Homodimers OPPORTUNITY: a randomized clinical trial of growth hormone on outcome in hemodialysis patients Prolactin Pro-Differentiation Pathway in Triple Negative Breast Cancer: Impact on Prognosis and Potential Therapy Impaired turnover of prolactin receptor contributes to transformation of human breast cells.Reevaluation of the proposed autocrine proliferative function of prolactin in breast cancer The oncogenic potential of autocrine human growth hormone in breast cancer.Prolactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment.New insights in prolactin: pathological implications.Prolactin and breast cancer: The need to avoid undertreatment of serious psychiatric illnesses in breast cancer patients: A review.Progesterone receptors (PR) mediate STAT actions: PR and prolactin receptor signaling crosstalk in breast cancer models.CAML promotes prolactin-dependent proliferation of breast cancer cells by facilitating prolactin receptor signaling pathways.

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P2860

Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice.

http://www.wikidata.org/entity/Q37375570

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on December 1997

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Activation of the prolactin re ...... ary tumors in transgenic mice.

@en

Activation of the prolactin re ...... ary tumors in transgenic mice.

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type

label

Activation of the prolactin re ...... ary tumors in transgenic mice.

@en

Activation of the prolactin re ...... ary tumors in transgenic mice.

@nl

prefLabel

Activation of the prolactin re ...... ary tumors in transgenic mice.

@en

Activation of the prolactin re ...... ary tumors in transgenic mice.

@nl

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Journal of Clinical Investigation

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Activation of the prolactin re ...... mary tumors in transgenic mice

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Gebre-Medhin M

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Gritli-Linde A

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Isaksson OG

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Törnell J

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Wennbo H

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P2860

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes.

Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects.

Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action.

Regulation of insulin-like growth factor I gene expression by growth hormone.

Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model.

Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression.

Serum and pituitary concentrations of prolactin and growth hormone in mice during a twenty-four hour period.

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2744-2751

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scholarly article

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10.1172/JCI119820

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11

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9389738

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508478

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