Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
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The lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation.Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) miceA genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair familiesNovel therapeutic approaches to lupus glomerulonephritis: translating animal models to clinical practice.Activation and differentiation of autoreactive B-1 cells by interleukin 10 induce autoimmune hemolytic anemia in Fas-deficient antierythrocyte immunoglobulin transgenic miceHeat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/lpr mouse model of systemic lupus erythematosusThe spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/APO-1) mutations.Structure and function of Fas/Fas ligand.NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells.TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupusNaja naja atra Venom Protects against Manifestations of Systemic Lupus Erythematosus in MRL/lpr MiceActivation of rheumatoid factor-specific B cells is antigen dependent and occurs preferentially outside of germinal centers in the lupus-prone NZM2410 mouse modelGenetics of systemic autoimmunity in mouse models of lupus.Lessons from the NZM2410 model and related strains.Genetic basis of the complex pathological manifestations of collagen disease: lessons from MRL/lpr and related mouse models.The genetics of systemic lupus erythematosus: putting the pieces together.Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families with hemolytic anemia.Enhanced functional recovery in MRL/MpJ mice after spinal cord dorsal hemisection.Autoimmune lymphoproliferative syndrome type III: an indefinite disorder.Autoimmune lymphoproliferative syndrome type III, an indefinite disorder.Genetic dissection of age-related changes of immune function in mice.The NOD mouse as a model of SLE.Autocrine IFNγ controls the regulatory function of lymphoproliferative double negative T cellsMurine models of systemic lupus erythematosusEndothelial nitric oxide synthase reduces crescentic and necrotic glomerular lesions, reactive oxygen production, and MCP1 production in murine lupus nephritisA Tlr7 translocation accelerates systemic autoimmunity in murine lupus.Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis.The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production.Fas/FasL-mediated apoptosis and inflammation are key features of acute human spinal cord injury: implications for translational, clinical application.An epistatic effect of the female specific loci on the development of autoimmune vasculitis and antinuclear autoantibody in murine lupus.Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis.MRL Strains Have a BAFFR Mutation without Functional Consequence.Role of MHC-linked susceptibility genes in the pathogenesis of human and murine lupus.Reno-protective effect and mechanism study of Huang Lian Jie Du Decoction on lupus nephritis MRL/lpr miceLight chain editing generates polyreactive antibodies in chronic graft-versus-host reaction.Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasisMRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells.CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly.Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice.
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Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
@en
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
@nl
type
label
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
@en
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
@nl
prefLabel
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
@en
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
@nl
P2093
P2860
P356
P1476
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
@en
P2093
A N Theofilopoulos
P2860
P304
P356
10.1172/JCI1817
P407
P577
1998-02-01T00:00:00Z