25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.
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Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunityInfection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infectionSurfactant Lipids at the Host-Environment Interface. Metabolic Sensors, Suppressors, and Effectors of Inflammatory Lung DiseaseAn Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophagesAtherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculatureTissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophagesLiberating Chiral Lipid Mediators, Inflammatory Enzymes, and LIPID MAPS from Biological Grease.Comparative transcriptomic analysis reveals novel genes and regulatory mechanisms of Tetragenococcus halophilus in response to salt stress.KLF4 Regulation of Ch25h and LXR Mitigates Atherosclerosis Susceptibility.Lanosterol Modulates TLR4-Mediated Innate Immune Responses in MacrophagesThe Intracellular Cholesterol Landscape: Dynamic Integrator of the Immune Response.Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection.Metabolic Phenotypes of Response to Vaccination in Humans.Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.
P2860
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P2860
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.
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name
25-Hydroxycholesterol activate ...... nd translation in macrophages.
@en
25-Hydroxycholesterol activate ...... nd translation in macrophages.
@nl
type
label
25-Hydroxycholesterol activate ...... nd translation in macrophages.
@en
25-Hydroxycholesterol activate ...... nd translation in macrophages.
@nl
prefLabel
25-Hydroxycholesterol activate ...... nd translation in macrophages.
@en
25-Hydroxycholesterol activate ...... nd translation in macrophages.
@nl
P2093
P2860
P50
P356
P1476
25-Hydroxycholesterol activate ...... nd translation in macrophages.
@en
P2093
Aaron F Carlin
Alfred H Merrill
Andrea Crotti
Casey E Romanoski
Christian R H Raetz
Christopher S Morello
Donna Reichart
Douglas R Cavener
H Alex Brown
Jeffrey G McDonald
P2860
P304
35812-35823
P356
10.1074/JBC.M113.519637
P407
P50
P577
2013-11-04T00:00:00Z