Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals.
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Themis, a T cell-specific protein important for late thymocyte developmentNotch signaling in CD4 and CD8 T cell developmentCentral tolerance: learning self-control in the thymusPresenilins regulate alphabeta T cell development by modulating TCR signalingLow ligand requirement for deletion and lack of synapses in positive selection enforce the gauntlet of thymic T cell maturation.Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns.FoxM1, a forkhead transcription factor is a master cell cycle regulator for mouse mature T cells but not double positive thymocytesCoupling of the cell cycle and apoptotic machineries in developing T cells.Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis.Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection.The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytesNotch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient miceInhibition of Notch signaling by a γ-secretase inhibitor attenuates hepatic fibrosis in rats.Notch signalling inhibits CD4 expression during initiation and differentiation of human T cell lineage.RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines.Chromatin remodeling complex NURF regulates thymocyte maturation.Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.Cytohesin binder and regulator (cybr) is not essential for T- and dendritic-cell activation and differentiationNotch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-mycImpairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profilingNotch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation.CCR7/CCL19 controls expression of EDG-1 in T cells.Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytesRegulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions.TCR and Notch signaling in CD4 and CD8 T-cell development.Dynamic repositioning of CD4 and CD8 genes during T cell development.Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice.Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signalingNotch1 signaling in FIZZ1 induction of myofibroblast differentiationPre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.Getting a GRASP on CASP: properties and role of the cytohesin-associated scaffolding protein in immunity.Thymic OX40 expression discriminates cells undergoing strong responses to selection ligands.Cutting Edge: Ikaros null thymocytes mature into the CD4 lineage with reduced TCR signal: A study using CD3{zeta} immunoreceptor tyrosine-based activation motif transgenic mice.Ikaros regulates Notch target gene expression in developing thymocytes.Dnmt3a regulates T-cell development and suppresses T-ALL transformation.Identification of genes involved in positive selection of CD4+8+ thymocytes: expanding the inventory.E protein transcription factors are required for the development of CD4(+) lineage T cells.Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase.The ins and outs of CCR7 in the thymus.Nur77 Regulates Nondeletional Mechanisms of Tolerance in T Cells.
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Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 March 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Distinct transcriptional progr ...... nd positive selection signals.
@en
Distinct transcriptional progr ...... nd positive selection signals.
@nl
type
label
Distinct transcriptional progr ...... nd positive selection signals.
@en
Distinct transcriptional progr ...... nd positive selection signals.
@nl
prefLabel
Distinct transcriptional progr ...... nd positive selection signals.
@en
Distinct transcriptional progr ...... nd positive selection signals.
@nl
P2093
P2860
P356
P1476
Distinct transcriptional progr ...... and positive selection signals
@en
P2093
Astar Winoto
Dongling Li
Ellen A Robey
P2860
P304
P356
10.1073/PNAS.0401133101
P407
P50
P577
2004-03-25T00:00:00Z