Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells
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Regulation of STATs by polycystin-1 and their role in polycystic kidney diseaseRegulation of Multi-drug Resistance in hepatocellular carcinoma cells is TRPC6/Calcium Dependent.Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapyThe PIM kinases in hematological cancersSTAT3 negatively regulates thyroid tumorigenesisInflammation and oncogenesis: a vicious connection.Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.Binding of galectin-1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells.Suppression of STAT3 and HIF-1 alpha mediates anti-angiogenic activity of betulinic acid in hypoxic PC-3 prostate cancer cells.mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immunotherapeutic responses.A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.Analysis of tumor environmental response and oncogenic pathway activation identifies distinct basal and luminal features in HER2-related breast tumor subtypes.HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathwayCharacterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinomaMicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine.Salternamide A Suppresses Hypoxia-Induced Accumulation of HIF-1α and Induces Apoptosis in Human Colorectal Cancer Cells.Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factRedox control of inflammation in macrophages.PPARγ regulated CIDEA affects pro-apoptotic responses in glioblastoma.Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cellsLeptin signaling is required for augmented therapeutic properties of mesenchymal stem cells conferred by hypoxia preconditioning.STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cellsGuggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3The role of tumor-associated macrophages in tumor vascularization.Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism.Vanillin Suppresses Cell Motility by Inhibiting STAT3-Mediated HIF-1α mRNA Expression in Malignant Melanoma CellsSTAT3: a target to enhance antitumor immune response.Myeloid cell diversification and complexity: an old concept with new turns in oncology.Molecular mechanisms regulating macrophage response to hypoxia.STAT3 signaling in pulmonary arterial hypertension.Oxidative metabolism in cancer: A STAT affair?STAT3 Target Genes Relevant to Human Cancers.Vascular remodeling process in pulmonary arterial hypertension, with focus on miR-204 and miR-126 (2013 Grover Conference series).Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug ResistanceA novel anti-viral role for STAT3 in IFN-α signalling responses.Dexamethasone downregulates expression of carbonic anhydrase IX via HIF-1α and NF-κB-dependent mechanisms.STAT3 regulates hypoxia-induced epithelial mesenchymal transition in oesophageal squamous cell cancer
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Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Signal transducer and activato ...... tumor-associated myeloid cells
@en
Signal transducer and activato ...... umor-associated myeloid cells.
@nl
type
label
Signal transducer and activato ...... tumor-associated myeloid cells
@en
Signal transducer and activato ...... umor-associated myeloid cells.
@nl
prefLabel
Signal transducer and activato ...... tumor-associated myeloid cells
@en
Signal transducer and activato ...... umor-associated myeloid cells.
@nl
P2093
P2860
P1476
Signal transducer and activato ...... tumor-associated myeloid cells
@en
P2093
Guilian Niu
Heehyoung Lee
Jiehui Deng
Jon Briggs
Maciej Kujawski
Marcin Kortylewski
Richard Jove
W Douglas Cress
P2860
P304
P356
10.1158/1541-7786.MCR-07-2177
P577
2008-07-01T00:00:00Z