Recent progress in protein drug design and discovery with a focus on novel approaches to the development of anti-cocaine medications.
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Modeling of pharmacokinetics of cocaine in human reveals the feasibility for development of enzyme therapies for drugs of abuseDesign of high-activity mutants of human butyrylcholinesterase against (-)-cocaine: structural and energetic factors affecting the catalytic efficiency.Butyrylcholinesterase levels and subjective effects of smoked cocaine in healthy cocaine usersPreparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine.Enzyme-therapy approaches for the treatment of drug overdose and addiction.Modeling in vitro inhibition of butyrylcholinesterase using molecular docking, multi-linear regression and artificial neural network approachesEpigenetics: a link between addiction and social environment.Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine.
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P2860
Recent progress in protein drug design and discovery with a focus on novel approaches to the development of anti-cocaine medications.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Recent progress in protein dru ...... t of anti-cocaine medications.
@en
Recent progress in protein dru ...... t of anti-cocaine medications.
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type
label
Recent progress in protein dru ...... t of anti-cocaine medications.
@en
Recent progress in protein dru ...... t of anti-cocaine medications.
@nl
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Recent progress in protein dru ...... t of anti-cocaine medications.
@en
Recent progress in protein dru ...... t of anti-cocaine medications.
@nl
P2860
P356
P1476
Recent progress in protein dru ...... t of anti-cocaine medications.
@en
P2093
Chang-Guo Zhan
Fang Zheng
P2860
P304
P356
10.4155/FMC.09.20
P577
2009-06-01T00:00:00Z