Transcriptomes of the major human pancreatic cell types.
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Concise review: in search of unlimited sources of functional human pancreatic beta cellsTranscriptional and epigenetic regulation in human isletsQuantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogrammingHuman pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetesINS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cellsReconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data.Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo.The Missing lnc(RNA) between the pancreatic β-cell and diabetesThe pancreatic β-cell transcriptome and integrated-omics.Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolismResearch resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome.The human pancreas proteome defined by transcriptomics and antibody-based profiling.Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMPBoth PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes.Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate pancreas function.An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development.TASK-1 Potassium Channels Limit Pancreatic α-Cell Calcium Influx and Glucagon Secretion.DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.Novel surface markers directed against adult human gallbladderOrganogenesis and functional genomics of the endocrine pancreasAssociation between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 StudyDeconstructing pancreas developmental biology.The pancreatic beta cell surface proteome.Rapid, high efficiency isolation of pancreatic ß-cells.EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells.Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.Profiling Eph receptor expression in cells and tissues: a targeted mass spectrometry approachIslet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell typesUse of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells.Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells.Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells.Identification of tissue-specific cell death using methylation patterns of circulating DNAStress-impaired transcription factor expression and insulin secretion in transplanted human islets.Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.Inhibition of DYRK1A Stimulates Human β-Cell Proliferation
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Transcriptomes of the major human pancreatic cell types.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on September 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transcriptomes of the major human pancreatic cell types.
@en
Transcriptomes of the major human pancreatic cell types.
@nl
type
label
Transcriptomes of the major human pancreatic cell types.
@en
Transcriptomes of the major human pancreatic cell types.
@nl
prefLabel
Transcriptomes of the major human pancreatic cell types.
@en
Transcriptomes of the major human pancreatic cell types.
@nl
P2093
P2860
P1433
P1476
Transcriptomes of the major human pancreatic cell types
@en
P2093
C J Stoeckert
K H Kaestner
O Smirnova
P R Streeter
P S Canaday
P2860
P2888
P304
P356
10.1007/S00125-011-2283-5
P577
2011-09-01T00:00:00Z