EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma.
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Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targetingMolecular mechanisms of ETS transcription factor-mediated tumorigenesisUnderstanding the Biology of Bone Sarcoma from Early Initiating Events through Late Events in Metastasis and Disease ProgressionChildren's Oncology Group's 2013 blueprint for research: bone tumorsPotential approaches to the treatment of Ewing's sarcomaClinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology GroupEwing Sarcoma, an enigmatic malignancy of likely progenitor cell origin, driven by transcription factor oncogenic fusions.Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growthEwing sarcoma EWS protein regulates midzone formation by recruiting Aurora B kinase to the midzoneEmergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.Cell Cycle Deregulation in Ewing's Sarcoma PathogenesisLong noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis.Synthesis and structure-activity relationship studies of small molecule disruptors of EWS-FLI1 interactions in Ewing's sarcoma.Ewing sarcoma ewsa protein regulates chondrogenesis of Meckel's cartilage through modulation of Sox9 in zebrafish.Meningeal Ewing Sarcoma/Peripheral PNET: Clinicopathological, Immunohistochemical and FISH study of four cases.RanBPM expression regulates transcriptional pathways involved in development and tumorigenesis.Recent advances in the molecular pathogenesis of Ewing's sarcoma.Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets.Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma CellsOncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma.The dual inhibitory effect of thiostrepton on FoxM1 and EWS/FLI1 provides a novel therapeutic option for Ewing's sarcomaMicroRNA function and dysregulation in bone tumors: the evidence to dateMinireview: role of orphan nuclear receptors in cancer and potential as drug targetsGene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma.The orphan nuclear receptors at their 25-year reunion.Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.EWS/FLI1 Target Genes and Therapeutic Opportunities in Ewing Sarcoma.microRNA and Bone Cancer.Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma.Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma.The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation.Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription FactorMicrosatellites with macro-influence in ewing sarcomaEwing's Sarcoma: Development of RNA Interference-Based Therapy for Advanced Disease.Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.RETRACTED: Pediatric sarcomas.
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P2860
EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
EWS/FLI and its downstream tar ...... ncogenesis in Ewing's sarcoma.
@en
EWS/FLI and its downstream tar ...... ncogenesis in Ewing's sarcoma.
@nl
type
label
EWS/FLI and its downstream tar ...... ncogenesis in Ewing's sarcoma.
@en
EWS/FLI and its downstream tar ...... ncogenesis in Ewing's sarcoma.
@nl
prefLabel
EWS/FLI and its downstream tar ...... ncogenesis in Ewing's sarcoma.
@en
EWS/FLI and its downstream tar ...... ncogenesis in Ewing's sarcoma.
@nl
P2093
P2860
P1433
P1476
EWS/FLI and its downstream tar ...... ncogenesis in Ewing's sarcoma.
@en
P2093
Anita K Iyer
Edward R B McCabe
Michelle Kinsey
Richard Smith
Stephen L Lessnick
P2860
P304
P356
10.1158/0008-5472.CAN-09-1540
P407
P577
2009-11-17T00:00:00Z