Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
about
The regulation of hematopoietic stem cell populationsStem Cell Ribonomics: RNA-Binding Proteins and Gene Networks in Stem Cell DifferentiationFunctional Integration of mRNA Translational Control ProgramsFunctional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins.Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.Neural stem and progenitor cell fate transition requires regulation of Musashi1 function.Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell stateUMG Lenti: novel lentiviral vectors for efficient transgene- and reporter gene expression in human early hematopoietic progenitors.TGF-β signaling and its role in the regulation of hematopoietic stem cells.RNA binding proteins in spermatogenesis: an in depth focus on the Musashi family.Blood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization: Biophysical regulation of hematopoietic differentiation and trafficking.Regulation of stress-induced hematopoiesisTransformation of the intestinal epithelium by the MSI2 RNA-binding protein.Preclinical activity of the novel B-cell-specific Moloney murine leukemia virus integration site 1 inhibitor PTC-209 in acute myeloid leukemia: Implications for leukemia therapyMSI2 is required for maintaining activated myelodysplastic syndrome stem cells.Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migrationMusashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis.RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survivalMsi RNA-binding proteins control reserve intestinal stem cell quiescence.Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.Polymorphisms of the TGF-β1 gene and the risk of acquired aplastic anemia in a Chinese population.Natural course and biology of CML.RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemia.Musashi-2 promotes migration and invasion in bladder cancer via activation of the JAK2/STAT3 pathway.Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins.Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets.Deconstructing the Complexity of TGFβ Signaling in Hematopoietic Stem Cells: Quiescence and Beyond.Stem Cells, Cancer, and MUSASHI in Blood and Guts.Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2.MUSASHI-2 duels in myelodysplastic syndromes.p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation.Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hh Signaling Pathway.The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis.Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA.SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling.
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Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
@en
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs.
@nl
type
label
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
@en
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs.
@nl
prefLabel
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
@en
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs.
@nl
P2093
P2860
P50
P356
P1476
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
@en
P2093
Benjamin L Ebert
Fatima Al-Shahrour
Patrick Tivnan
Raquel P Deering
Sun-Mi Park
P2860
P356
10.1084/JEM.20130736
P407
P577
2014-01-06T00:00:00Z