β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
about
Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyReport from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell ReplacementWolfram Syndrome: Diagnosis, Management, and TreatmentModeling Kidney Disease with iPS CellsDissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing toolsRole of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram SyndromeNatural history of β-cell adaptation and failure in type 2 diabetesToward beta cell replacement for diabetesA novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors.Induced Pluripotent Stem Cells: Global Research Trends.Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells.The pancreatic β cell: recent insights from human genetics.A calcium-dependent protease as a potential therapeutic target for Wolfram syndromeResearch resource: Monitoring endoplasmic reticulum membrane integrity in β-cells at the single-cell level.Getting the better of ER stress.Phenotype Prediction of Pathogenic Nonsynonymous Single Nucleotide Polymorphisms in WFS1Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.Wolfram syndrome iPS cells: the first human cell model of endoplasmic reticulum diseaseRole of the unfolded protein response in β cell compensation and failure during diabetes.An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery.When is it MODY? Challenges in the Interpretation of Sequence Variants in MODY Genes.Monogenic diabetes: Implementation of translational genomic research towards precision medicine.Is Transforming Stem Cells to Pancreatic Beta Cells Still the Holy Grail for Type 2 Diabetes?Endoplasmic Reticulum (ER) Stress and Endocrine Disorders.Phenylbutyrate and β-cell function: contribution of histone deacetylases and ER stress inhibition.iPSC technology-based regenerative therapy for diabetes.Generation of stem cell-derived β-cells from patients with type 1 diabetes.Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells.Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease.Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro.Diabetes: Targeting endoplasmic reticulum to combat juvenile diabetesStem Cell-Derived Beta Cells for Treatment of Type 1 Diabetes?Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.Emerging Roles for Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) in Pancreatic Beta Cells and Diabetes
P2860
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P2860
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
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name
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
@en
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
@nl
type
label
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
@en
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
@nl
prefLabel
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
@en
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
@nl
P2093
P2860
P356
P1433
P1476
β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
@en
P2093
Charles LeDuc
David J Kahler
Haiqing Hua
Hector Martinez
Kazuhisa Watanabe
Linshan Shang
Matthew Freeby
Matthew Zimmer
Rudolph L Leibel
P2860
P304
P356
10.2337/DB13-0717
P407
P577
2013-11-13T00:00:00Z