Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.
about
Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cellsA novel regulatory mechanism links PLCγ1 to PDK1Phosphoinositides: tiny lipids with giant impact on cell regulationRac Regulates Its Effector Phospholipase C 2 through Interaction with a Split Pleckstrin Homology DomainThe phospholipase C isozymes and their regulationGPVI and integrin alphaIIb beta3 signaling in plateletsA respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signalingRole of Src homology domain binding in signaling complexes assembled by the murid γ-herpesvirus M2 protein.Quantification of gel-separated proteins and their phosphorylation sites by LC-MS using unlabeled internal standards: analysis of phosphoprotein dynamics in a B cell lymphoma cell line.Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C γ2 (PLCγ2) using TRPM7-kinase.Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-gamma1.BTK inhibitors in chronic lymphocytic leukemia: a glimpse to the future.Protein kinases: emerging therapeutic targets in chronic lymphocytic leukemia.The defect of SFRP2 modulates an influx of extracellular calcium in B lymphocytes.The role of SH3BP2 in the pathophysiology of cherubism.Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library.Phospholipase Cγ2 plays a role in TCR signal transduction and T cell selection.Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigenNovel Bruton's tyrosine kinase inhibitors currently in development.Clinical potential of targeting Bruton's tyrosine kinase.Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release.Syk and pTyr'd: Signaling through the B cell antigen receptorQuantitative time-resolved phosphoproteomic analysis of mast cell signaling.Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity.B-lymphocyte tolerance and effector function in immunity and autoimmunity.Does B cell receptor signaling in chronic lymphocytic leukaemia cells differ from that in other B cell types?BTK Signaling in B Cell Differentiation and Autoimmunity.Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex.Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model.Low and nontoxic inorganic mercury burdens attenuate BCR-mediated signal transduction.Mechanosensitive activation of K+ channel via phospholipase C-induced depletion of phosphatidylinositol 4,5-bisphosphate in B lymphocytes.Analysis of amphotericin B-induced cell signaling with chemical inhibitors of signaling molecules.Isozyme-specific stimulation of phospholipase C-gamma2 by Rac GTPases.Autoimmune disease-associated haplotypes of BLK exhibit lowered thresholds for B cell activation and expansion of Ig class-switched B cells.Inhibition of IgE-mediated secretion from human basophils with a highly selective Bruton's tyrosine kinase, Btk, inhibitor.Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome.Signaling by the B Cell Receptor (BCR)Antigen activates B Cell Receptor (BCR) leading to generation of second messengersRole of Bruton's tyrosine kinase in B cells and malignancies.Signalosomes assemble at the activated BCR
P2860
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P2860
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Mechanism of B-cell receptor-i ...... ion of phospholipase C-gamma2.
@en
Mechanism of B-cell receptor-i ...... ion of phospholipase C-gamma2.
@nl
type
label
Mechanism of B-cell receptor-i ...... ion of phospholipase C-gamma2.
@en
Mechanism of B-cell receptor-i ...... ion of phospholipase C-gamma2.
@nl
prefLabel
Mechanism of B-cell receptor-i ...... ion of phospholipase C-gamma2.
@en
Mechanism of B-cell receptor-i ...... ion of phospholipase C-gamma2.
@nl
P2093
P2860
P1476
Mechanism of B-cell receptor-i ...... ion of phospholipase C-gamma2.
@en
P2093
Benoit Poulin
Fujio Sekiya
Sue Goo Rhee
Yeun Ju Kim
Yun Soo Bae
P2860
P304
P356
10.1128/MCB.24.22.9986-9999.2004
P407
P577
2004-11-01T00:00:00Z