The membrane proximal region of the cannabinoid receptor CB1 N-terminus can allosterically modulate ligand affinity.
about
High-resolution crystal structure of the human CB1 cannabinoid receptor.Crystal Structure of the Human Cannabinoid Receptor CB1.Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB1.Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.In silico mapping of allosteric ligand binding sites in type-1 cannabinoid receptor.Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor.Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities.Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity.Dynamic roles for the N-terminus of the yeast G protein-coupled receptor Ste2p.
P2860
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P2860
The membrane proximal region of the cannabinoid receptor CB1 N-terminus can allosterically modulate ligand affinity.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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name
The membrane proximal region o ...... ally modulate ligand affinity.
@en
The membrane proximal region o ...... ally modulate ligand affinity.
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type
label
The membrane proximal region o ...... ally modulate ligand affinity.
@en
The membrane proximal region o ...... ally modulate ligand affinity.
@nl
prefLabel
The membrane proximal region o ...... ally modulate ligand affinity.
@en
The membrane proximal region o ...... ally modulate ligand affinity.
@nl
P2860
P921
P356
P1433
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The membrane proximal region o ...... ally modulate ligand affinity.
@en
P2093
David L Farrens
Jonathan F Fay
P2860
P304
P356
10.1021/BI400842K
P407
P577
2013-11-08T00:00:00Z