Identification and characterization of the neurofibromatosis type 1 protein product.
about
Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformationMouse models of neurofibromatosis 1 and 2.Alternative splicing of the neurofibromatosis type I pre-mRNAActivated Ras as a Therapeutic Target: Constraints on Directly Targeting Ras Isoforms and Wild-Type versus Mutated ProteinsThe motor protein kinesin-1 links neurofibromin and merlin in a common cellular pathway of neurofibromatosisAblation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brainPhosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortexIn vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndromeNeurofibromatosis: chronological history and current issues.Spinal deformity in neurofibromatosis type-1: diagnosis and treatment.Clinical and genetic patterns of neurofibromatosis 1 and 2.Familial neurofibromatosis type 1 associated with an overgrowth syndrome resembling Weaver syndrome.Neurofibromin-deficient fibroblasts fail to form perineurium in vitro.Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein.Structural analysis of the GAP-related domain from neurofibromin and its implicationsIdentification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity.The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology.Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation.Neurofibromin in the brain.Repression of the NF1 gene by Tax may expain the development of neurofibromas in human T-lymphotropic virus type 1 transgenic mice.Skin-derived precursor cells as an in vitro modelling tool for the study of type 1 neurofibromatosisOptic pathway gliomas in neurofibromatosis-1: controversies and recommendations.Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutationsReview: low-grade gliomas as neurodevelopmental disorders: insights from mouse models of neurofibromatosis-1.Inhibition and termination of physiological responses by GTPase activating proteins.Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin.Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids.Neurofibromatosis type 1: pathology, clinical features and molecular genetics.The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.Differential regulation of cellular activities by GTPase-activating protein and NF1.Specific expression of the neurofibromatosis type 1 gene (NF1) in the hamster Schwann cell.Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function.Molecular genetic analysis of the von Recklinghausen neurofibromatosis (NF1) gene using polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) method.Sequential modification of serines 621 and 624 in the Raf-1 carboxyl terminus produces alterations in its electrophoretic mobility.GTPase stimulation in shrimp Ras(Q(61)K) with geranylgeranyl pyrophosphate but not mammalian GAP.Genotype-Phenotype Correlation in NF1: Evidence for a More Severe Phenotype Associated with Missense Mutations Affecting NF1 Codons 844-848.Differential contribution of M(r) 120 kDa rasGTPase-activating protein and neurofibromatosis type 1 gene product during the transition from growth phase to arrested state in human fibroblasts accompanied by a unique rasGTPase-activating activity.Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development.Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.Developmental regulation of a neuron-specific neurofibromatosis 1 isoform.
P2860
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P2860
Identification and characterization of the neurofibromatosis type 1 protein product.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Identification and characterization of the neurofibromatosis type 1 protein product.
@en
Identification and characterization of the neurofibromatosis type 1 protein product.
@nl
type
label
Identification and characterization of the neurofibromatosis type 1 protein product.
@en
Identification and characterization of the neurofibromatosis type 1 protein product.
@nl
prefLabel
Identification and characterization of the neurofibromatosis type 1 protein product.
@en
Identification and characterization of the neurofibromatosis type 1 protein product.
@nl
P2093
P2860
P356
P1476
Identification and characterization of the neurofibromatosis type 1 protein product.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.22.9914
P407
P577
1991-11-01T00:00:00Z