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Pain as a channelopathyTowards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium ChannelsThe perception and endogenous modulation of painLocating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channelStructure-based assessment of disease-related mutations in human voltage-gated sodium channels.Aberrant plasticity of peripheral sensory axons in a painful neuropathyA novel behavioral assay for measuring cold sensation in mice.Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons.Systematic study of binding of μ-conotoxins to the sodium channel NaV1.4.Linkage between increased nociception and olfaction via a SCN9A haplotypeAdult ciliary epithelial stem cells generate functional neurons and differentiate into both early and late born retinal neurons under non-cell autonomous influences.Dexmedetomidine inhibits Tetrodotoxin-resistant Nav1.8 sodium channel activity through Gi/o-dependent pathway in rat dorsal root ganglion neurons.Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons.Pharmacogenetics of analgesic drugsSCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing.Topical Tetrodotoxin Attenuates Photophobia Induced by Corneal Injury in the Rat.Marked difference in saxitoxin and tetrodotoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1.7) [corrected]Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics?Inflammatory and neuropathic cold allodynia are selectively mediated by the neurotrophic factor receptor GFRα3Novel mutations mapping to the fourth sodium channel domain of Nav1.7 result in variable clinical manifestations of primary erythromelalgiaIdentification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6.β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells.Nature and nurture of human pain.Gain-of-function mutations in SCN11A cause familial episodic pain.The fundamental unit of pain is the cell.Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.Biallelic SCN10A mutations in neuromuscular disease and epileptic encephalopathy.The discovery and development of analgesics: new mechanisms, new modalities.Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies.Human Mendelian pain disorders: a key to discovery and validation of novel analgesics.Mutational consequences of aberrant ion channels in neurological disorders.Genotype phenotype associations across the voltage-gated sodium channel family.Neuroplasticity of ascending and descending pathways after somatosensory system injury: reviewing knowledge to identify neuropathic pain therapeutic targets.The effect of Ringer's solution within a dressing to elicit pain relief.Functional up-regulation of Nav1.8 sodium channel in Aβ afferent fibers subjected to chronic peripheral inflammation.Predictive 3D modelling of the interactions of pyrethroids with the voltage-gated sodium channels of ticks and mites.Stromal Cell-Derived Factor 1 Increases Tetrodotoxin-Resistant Sodium Currents Nav1.8 and Nav1.9 in Rat Dorsal Root Ganglion Neurons via Different Mechanisms.Antihyperalgesic effects of ProTx-II, a Nav1.7 antagonist, and A803467, a Nav1.8 antagonist, in diabetic mice.Sodium channel slow inactivation interferes with open channel block.Erythromelalgia mutation Q875E Stabilizes the activated state of sodium channel Nav1.7.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 January 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Sodium channelopathies and pain.
@en
Sodium channelopathies and pain.
@nl
type
label
Sodium channelopathies and pain.
@en
Sodium channelopathies and pain.
@nl
prefLabel
Sodium channelopathies and pain.
@en
Sodium channelopathies and pain.
@nl
P50
P1433
P1476
Sodium channelopathies and pain.
@en
P2093
Andreas Leffler
P2860
P2888
P304
P356
10.1007/S00424-009-0779-3
P577
2010-01-26T00:00:00Z