ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97. - Wikidata - awgldk - TriplyDB

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

http://www.wikidata.org/entity/Q37687114

about

Fundamental Characteristics of AAA+ Protein Family Structure and Function Positive cooperativity of the p97 AAA ATPase is critical for essential functions Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48.Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain.The complexities of p97 function in health and disease Mak5 and Ebp2 act together on early pre-60S particles and their reduced functionality bypasses the requirement for the essential pre-60S factor Nsa1.The power of AAA-ATPases on the road of pre-60S ribosome maturation--molecular machines that strip pre-ribosomal particles Protective role of cell division cycle 48 (CDC48) protein against neurodegeneration via ubiquitin-proteasome system dysfunction during zebrafish development Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy.Structure and Function of p97 and Pex1/6 Type II AAA+ Complexes.Biological and Pathological Implications of an Alternative ATP-Powered Proteasomal Assembly With Cdc48 and the 20S Peptidase.

P2860

Q28066287-73390854-3027-4373-80A7-B339911421B3 Q28308130-A0F851DC-8DB3-4BDA-837B-DDF36ED71A4C Q33905679-01CE3D37-F180-4D95-A869-DE918F00D496 Q33916854-44685C4F-271A-4259-802B-B6C8BBD586FC Q34506519-1BF2598E-1050-4E15-8EDB-7E4F3868D796 Q34632255-EE33F698-1CD5-41C1-841E-41A69F68DD2D Q35061568-4FEF7532-48BB-4E00-A7D2-D0185E270837 Q35690797-422D69F4-93AF-4A8C-BA91-5E902B35ECB9 Q36080410-946D6323-FCD5-444C-AEFF-5F305ED351E7 Q38648242-2FBFBBB6-4520-49E4-91A4-01AE6A9F83BF Q38682988-E35260E9-F5AF-4A6E-836E-61F414BB7CDF Q39371142-60490512-AFF7-42C9-AA5A-5D483D8ECF20 Q55363518-30704930-CB75-4C5D-BAA5-3F3889BD9C61

P2860

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

http://www.wikidata.org/entity/Q37687114

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on February 2010

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

@en

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

@nl

type

label

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

@en

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

@nl

prefLabel

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

@en

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

@nl

P1433

Q37687114-25D52E4F-B2C4-4B42-8F18-3A3A65814FE5

P1476

Q37687114-ABE9E366-8BB6-4695-99B1-2131254F8609

P2093

Q37687114-7E2FB308-F3EA-4C03-ABEC-8435B778CD85

Q37687114-9C271503-E8B3-4215-A717-D403324402CC

P2860

Q37687114-01C5C055-2BCA-4824-AFC8-906E71EACC9C

Q37687114-06B29B1E-365C-4811-807B-6E6B833C02E0

Q37687114-18146C27-F756-4ED4-BF54-B05D0C1CA7ED

Q37687114-1FD05AC9-389D-4126-B538-514F9E016BA7

Q37687114-21075AA1-3A96-47DE-AE14-26F6C7ACA6FC

Q37687114-22E722AD-0E57-4F39-8288-157844F0C6CE

Q37687114-2842B48D-18B5-4384-8096-BA09EA1E74EB

Q37687114-2D36D8F1-02ED-448B-BEFF-0E3024DED05F

Q37687114-3CD7ABA0-8607-4D36-BCF7-E2F7E08A7111

Q37687114-4044484C-2A7F-4D98-B42F-EB50475FC406

P304

Q37687114-E64404C8-661F-48DC-B186-69579366D247

P31

Q37687114-D6F46126-14AE-4AA6-A1C6-E40571D4ABB2

P356

Q37687114-A35A0AE3-EB0E-45B4-9D25-E3A0500DBEB6

P433

Q37687114-80944C89-4B04-4243-9062-AED46DF8851C

P478

Q37687114-D1C6AA28-343F-4580-B70A-26AAF569C311

P577

Q37687114-4BEADBCF-F022-45DB-AA92-CD2F16B839B6

P5875

Q37687114-81429B8E-55F2-4C2E-9E95-D965779D94FA

P698

Q37687114-E02AA711-D839-4E22-A488-6E5952739D0E

P356

P1433

Biochemistry and Cell Biology

P1476

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

@en

P2093

Masatoshi Esaki

http://www.w3.org/2001/XMLSchema#string

Teru Ogura

http://www.w3.org/2001/XMLSchema#string

P2860

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change

Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities

Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells

Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains

ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity

Nucleotide dependent motion and mechanism of action of p97/VCP

Central pore residues mediate the p97/VCP activity required for ERAD

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

P304

109-117

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1139/O09-116

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

88

http://www.w3.org/2001/XMLSchema#string

P577

2010-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41405571

http://www.w3.org/2001/XMLSchema#string

P698

20130684

http://www.w3.org/2001/XMLSchema#string