Genotoxicity testing: moving beyond qualitative "screen and bin" approach towards characterization of dose-response and thresholds.
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Advancing human health risk assessment: integrating recent advisory committee recommendationsContributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents.Regulatory requirements for genotoxicity assessment of plant protection product active ingredients, impurities, and metabolites.International regulatory requirements for genotoxicity testing for pharmaceuticals used in human medicine, and their impurities and metabolites.Dose-Response for Multiple Biomarkers of Exposure and Genotoxic Effect Following Repeated Treatment of Rats with the Alkylating Agents, MMS and MNU.Sublinear response in lacZ mutant frequency of Muta™ Mouse spermatogonial stem cells after low dose subchronic exposure to N-ethyl-N-nitrosourea.Quantitative relationships between lacZ mutant frequency and DNA adduct frequency in Muta™Mouse tissues and cultured cells exposed to 3-nitrobenzanthrone.Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.An integrative test strategy for cancer hazard identification.Quantitative approaches for assessing dose-response relationships in genetic toxicology studies.
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Genotoxicity testing: moving beyond qualitative "screen and bin" approach towards characterization of dose-response and thresholds.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Genotoxicity testing: moving b ...... dose-response and thresholds.
@en
Genotoxicity testing: moving b ...... dose-response and thresholds.
@nl
type
label
Genotoxicity testing: moving b ...... dose-response and thresholds.
@en
Genotoxicity testing: moving b ...... dose-response and thresholds.
@nl
prefLabel
Genotoxicity testing: moving b ...... dose-response and thresholds.
@en
Genotoxicity testing: moving b ...... dose-response and thresholds.
@nl
P2860
P356
P1476
Genotoxicity testing: moving b ...... dose-response and thresholds.
@en
P2093
B Bhaskar Gollapudi
Lynn H Pottenger
P2860
P304
P356
10.1002/EM.20612
P577
2010-10-01T00:00:00Z