Molecular dissection of the 5q deletion in myelodysplastic syndrome.
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The progress of early growth response factor 1 and leukemiaA novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclastsHaploinsufficient tumor suppressor genes.A novel insertion ins(18;5)(q21.1;q31.2q35.1) in acute myeloid leukemia associated with microdeletions at 5q31.2, 5q35.1q35.2 and 18q12.3q21.1 detected by oligobased array comparative genomic hybridizationRole of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders.Collateral Lethality: A new therapeutic strategy in oncologyRigosertib as a selective anti-tumor agent can ameliorate multiple dysregulated signaling transduction pathways in high-grade myelodysplastic syndrome.Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells.Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc.Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice.Spliceosome and other novel mutations in chronic lymphocytic leukemia and myeloid malignancies.Sclerotic lesions of the spine: MRI assessment.β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q).The molecular mechanism of thalidomide analogs in hematologic malignancies.Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis.Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletionVan den Berghe's 5q- syndrome and myelodysplastic syndrome with isolated del(5q).Germline polymorphisms and survival of lung adenocarcinoma patients: a genome-wide study in two European patient series.Transcription factors Fli1 and EKLF in the differentiation of megakaryocytic and erythroid progenitor in 5q- syndrome and in Diamond-Blackfan anemia.Age-related inflammatory bone marrow microenvironment induces ineffective erythropoiesis mimicking del(5q) MDS.Nuances of Morphology in Myelodysplastic Diseases in the Age of Molecular Diagnostics.The role of p53 in myelodysplastic syndromes and acute myeloid leukemia: molecular aspects and clinical implications.Isolated del(5q) in Patients Following Therapies for Various Malignancies May Not All Be Clinically Significant.
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Molecular dissection of the 5q deletion in myelodysplastic syndrome.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Molecular dissection of the 5q deletion in myelodysplastic syndrome.
@en
Molecular dissection of the 5q deletion in myelodysplastic syndrome.
@nl
type
label
Molecular dissection of the 5q deletion in myelodysplastic syndrome.
@en
Molecular dissection of the 5q deletion in myelodysplastic syndrome.
@nl
prefLabel
Molecular dissection of the 5q deletion in myelodysplastic syndrome.
@en
Molecular dissection of the 5q deletion in myelodysplastic syndrome.
@nl
P2860
P1433
P1476
Molecular dissection of the 5q deletion in myelodysplastic syndrome.
@en
P2093
Benjamin L Ebert
P2860
P304
P356
10.1053/J.SEMINONCOL.2011.04.010
P577
2011-10-01T00:00:00Z