Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism.
about
An immunology primer for computational modelersSulfamethoxazole induces a switch mechanism in T cell receptors containing TCRVβ20-1, altering pHLA recognitionThe growth threshold conjecture: a theoretical framework for understanding T-cell toleranceHighly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I MoleculeStructure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicityProline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptidesPeptide modulation of class I major histocompatibility complex protein molecular flexibility and the implications for immune recognition.Identification of swine influenza virus epitopes and analysis of multiple specificities expressed by cytotoxic T cell subsetsAssessing T cell clonal size distribution: a non-parametric approach.The basis for limited specificity and MHC restriction in a T cell receptor interface.Specific increase in potency via structure-based design of a TCR.Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes.Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity.An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry.The versatility of the αβ T-cell antigen receptor.Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade.TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility.Antiviral memory phenotype T cells in unexposed adults.Insights into immune structure, recognition, and signaling.The novel immunotherapeutic molecule T11TS modulates glioma-induced changes of key components of the immunological synapse in favor of T cell activation and glioma abrogation.A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor bindingSingle-molecule motions of MHC class II rely on bound peptides.Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex.The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.Polymorphisms of the FOXF1 and MHC locus genes in individuals undergoing esophageal acid reflux assessments.The versatility of the CD1 lipid antigen presentation pathway.NMR spectroscopy reveals unexpected structural variation at the protein-protein interface in MHC class I molecules.
P2860
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P2860
Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Structural and dynamic control ...... tivity, and binding mechanism.
@en
type
label
Structural and dynamic control ...... tivity, and binding mechanism.
@en
prefLabel
Structural and dynamic control ...... tivity, and binding mechanism.
@en
P2093
P2860
P1476
Structural and dynamic control ...... tivity, and binding mechanism.
@en
P2093
Brian M Baker
Daniel R Scott
Sydney J Blevins
William F Hawse
P2860
P356
10.1111/J.1600-065X.2012.01165.X
P577
2012-11-01T00:00:00Z