LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
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p38 MAPK and PI3K/AKT Signalling Cascades inParkinson's DiseaseSystems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor SystemDiagnostic Accuracy of Transcranial Sonography of the Substantia Nigra in Parkinson's disease: A Systematic Review and Meta-analysisLeucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brainIsobavachalcone Attenuates MPTP-Induced Parkinson's Disease in Mice by Inhibition of Microglial Activation through NF-κB PathwayA visual review of the interactome of LRRK2: Using deep-curated molecular interaction data to represent biology.Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration.Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.LRRK2 levels in immune cells are increased in Parkinson's diseaseA Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.Evidence of inflammatory system involvement in Parkinson's disease.Leucine-Rich Repeat Kinase 2 (Lrrk2) Deficiency Diminishes the Development of Experimental Autoimmune Uveitis (EAU) and the Adaptive Immune Response.Anti-inflammatory effects of thymoquinone in activated BV-2 microglial cells.Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem CellsThe Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease.Parkinson's disease and enhanced inflammatory response.Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons.Tollip, an early regulator of the acute inflammatory response in the substantia nigraLeucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na+/K+ ATPase Activity in Dendritic CellsTherapeutic strategies in Parkinson's disease: what we have learned from animal models.Inflammation in Parkinson's disease: role of glucocorticoids.Cellular processes associated with LRRK2 function and dysfunctionThe implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson's disease.Microglia-blood vessel interactions: a double-edged sword in brain pathologies.Leucine-rich repeat kinase 2 and Parkinson's disease.LRRK2 levels and phosphorylation in Parkinson's disease brain and cases with restricted Lewy bodies.Genetic Determinants of Parkinson's Disease: Can They Help to Stratify the Patients Based on the Underlying Molecular Defect?Electric stimulation of the vagus nerve reduced mouse neuroinflammation induced by lipopolysaccharide.Association of TLR4 gene polymorphisms with sporadic Parkinson's disease in a Han Chinese population.Irisflorentin improves α-synuclein accumulation and attenuates 6-OHDA-induced dopaminergic neuron degeneration, implication for Parkinson's disease therapy.Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.Rab GTPases in Immunity and InflammationLeucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells.Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan.Th17 Cells Induce Dopaminergic Neuronal Death via LFA-1/ICAM-1 Interaction in a Mouse Model of Parkinson's Disease.The kinase LRRK2 is differently expressed in chronic rhinosinusitis with and without nasal polyps.Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease.Association Between Peripheral Inflammation and DATSCAN Data of the Striatal Nuclei in Different Motor Subtypes of Parkinson Disease.Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4
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LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
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type
label
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
@en
prefLabel
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
@en
P2860
P921
P356
P1476
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?
@en
P2093
Elisa Greggio
P2860
P2888
P356
10.1186/1742-2094-11-52
P5008
P577
2014-03-21T00:00:00Z
P5875
P6179
1002874050