Cellular processes associated with LRRK2 function and dysfunction
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LRRK2 inhibitors and their potential in the treatment of Parkinson's disease: current perspectivesLRRK2 phosphorylation level correlates with abnormal motor behaviour in an experimental model of levodopa-induced dyskinesiasmTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1G2385R and I2020T Mutations Increase LRRK2 GTPase ActivityStructure, function, and leucine-rich repeat kinase 2: On the importance of reproducibility in understanding Parkinson's disease.Increased Oxidative Stress Markers in Cerebrospinal Fluid from Healthy Subjects with Parkinson's Disease-Associated LRRK2 Gene Mutations.LRRK2 and Autophagy.LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease.The LRRK2-macroautophagy axis and its relevance to Parkinson's diseaseGenetic Determinants of Parkinson's Disease: Can They Help to Stratify the Patients Based on the Underlying Molecular Defect?Exploring pre-degenerative alterations in humans using induced pluripotent stem cell-derived dopaminergic neurons.Neuroprotective Effect of the LRRK2 Kinase Inhibitor PF-06447475 in Human Nerve-Like Differentiated Cells Exposed to Oxidative Stress Stimuli: Implications for Parkinson's Disease.The melanoma-linked "redhead" MC1R influences dopaminergic neuron survival.Inventory of real world data sources in Parkinson's disease.The LRRK2 signalling system.Convergent pathways in Parkinson's disease.Achieving neuroprotection with LRRK2 kinase inhibitors in Parkinson disease.Translational approaches to restoring mitochondrial function in Parkinson's disease.Mechanisms of Mutant LRRK2 Neurodegeneration.Native DIGE proteomic analysis of mitochondria from substantia nigra and striatum during neuronal degeneration and its compensation in an animal model of early Parkinson's disease.Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease.LRRK2 Phosphorylation.Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2 G2019S -Parkinson's disease.In Vitro Modeling of Leucine-Rich Repeat Kinase 2 (LRRK2) G2019S-Mediated Parkinson's Disease Pathology.The Enzymatic Core of the Parkinson’s Disease-Associated Protein LRRK2 Impairs Mitochondrial Biogenesis in Aging Yeast.Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis
P2860
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P2860
Cellular processes associated with LRRK2 function and dysfunction
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Cellular processes associated with LRRK2 function and dysfunction
@en
type
label
Cellular processes associated with LRRK2 function and dysfunction
@en
prefLabel
Cellular processes associated with LRRK2 function and dysfunction
@en
P2860
P356
P1433
P1476
Cellular processes associated with LRRK2 function and dysfunction
@en
P2093
Rebecca Wallings
Rina Bandopadhyay
P2860
P304
P356
10.1111/FEBS.13305
P407
P577
2015-05-09T00:00:00Z
2015-08-01T00:00:00Z