CCAAT/enhancer-binding protein-beta is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene.
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ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase geneCharacterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter geneThe p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOPGlutamine-mediated dual regulation of heat shock transcription factor-1 activation and expressionTranscriptional Regulation of the Mitochondrial Citrate and Carnitine/Acylcarnitine Transporters: Two Genes Involved in Fatty Acid Biosynthesis and β-oxidation.Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathwayTranscriptional control of the human sodium-coupled neutral amino acid transporter system A gene by amino acid availability is mediated by an intronic element.Regulation of adipocyte 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) by CCAAT/enhancer-binding protein (C/EBP) β isoforms, LIP and LAP.Asparagine synthetase: regulation by cell stress and involvement in tumor biologyUpregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4.Asparagine synthetase chemotherapy.Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.Auto-activation of c-JUN gene by amino acid deprivation of hepatocellular carcinoma cells reveals a novel c-JUN-mediated signaling pathway.Transcriptional repression of ATF4 gene by CCAAT/enhancer-binding protein β (C/EBPβ) differentially regulates integrated stress response.Nutritional control of gene expression: how mammalian cells respond to amino acid limitation.Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription.Alignment of the transcription start site coincides with increased transcriptional activity from the human asparagine synthetase gene following amino acid deprivation of HepG2 cells.Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathwayDifferential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during theElevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements.Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation.Amino-acid limitation induces transcription from the human C/EBPbeta gene via an enhancer activity located downstream of the protein coding sequence.CCAAT/enhancer-binding protein-beta participates in insulin-responsive expression of the factor VII gene.Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized hiHuman CCAAT/enhancer-binding protein beta gene expression is activated by endoplasmic reticulum stress through an unfolded protein response element downstream of the protein coding sequence.Stable conditional expression and effect of C/ebpβ-LIP in adipocytes using the pSLIK system.Alu- and 7SL RNA Analogues Suppress MCF-7 Cell Viability through Modulating the Transcription of Endoplasmic Reticulum Stress Response Genes.Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2Elevated cJUN expression and an ATF/CRE site within the ATF3 promoter contribute to activation of ATF3 transcription by the amino acid response.Amino acid control of the human glyceraldehyde 3-phosphate dehydrogenase gene transcription in hepatocyte.Insulin regulates TRB3 and other stress-responsive gene expression through induction of C/EBPbeta.Transcriptional control of the arginine/lysine transporter, cat-1, by physiological stress.Characterization of the nutrient-sensing response unit in the human asparagine synthetase promoter.Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response.Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter.Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells.Methylation of the asparagine synthetase promoter in human leukemic cell lines is associated with a specific methyl binding protein.
P2860
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P2860
CCAAT/enhancer-binding protein-beta is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
CCAAT/enhancer-binding protein ...... an asparagine synthetase gene.
@en
type
label
CCAAT/enhancer-binding protein ...... an asparagine synthetase gene.
@en
prefLabel
CCAAT/enhancer-binding protein ...... an asparagine synthetase gene.
@en
P2093
P2860
P356
P1476
CCAAT/enhancer-binding protein ...... an asparagine synthetase gene.
@en
P2093
P2860
P304
48100-48107
P356
10.1074/JBC.M109533200
P407
P577
2001-10-24T00:00:00Z