Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth.
about
Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sitesThe DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.Limited repair of 8-hydroxy-7,8-dihydroguanine residues in human testicular cells.Recent aspects of oxidative DNA damage: guanine lesions, measurement and substrate specificity of DNA repair glycosylases.Influence of DNA torsional rigidity on excision of 7,8-dihydro-8-oxo-2'-deoxyguanosine in the presence of opposing abasic sites by human OGG1 proteinDelayed repair of radiation induced clustered DNA damage: friend or foe?Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesionsBase damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-terminiNon-problematic risks from low-dose radiation-induced DNA damage clustersReplication fork collapse is a major cause of the high mutation frequency at three-base lesion clustersIncreased mutability and decreased repairability of a three-lesion clustered DNA-damaged site comprised of an AP site and bi-stranded 8-oxoG lesions.Repair of clustered uracil DNA damages in Escherichia coli.Two clustered 8-oxo-7,8-dihydroguanine (8-oxodG) lesions increase the point mutation frequency of 8-oxodG, but do not result in double strand breaks or deletions in Escherichia coli.Enhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage siteProcessing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation.The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.
P2860
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P2860
Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Recognition and kinetics for e ...... hia coli proteins Fpg and Nth.
@en
type
label
Recognition and kinetics for e ...... hia coli proteins Fpg and Nth.
@en
prefLabel
Recognition and kinetics for e ...... hia coli proteins Fpg and Nth.
@en
P2093
P356
P1433
P1476
Recognition and kinetics for e ...... hia coli proteins Fpg and Nth.
@en
P2093
David-Cordonnier MH
P304
P356
10.1021/BI002605D
P407
P577
2001-05-01T00:00:00Z