Efficient siRNA selection using hybridization thermodynamics.
about
Designing of highly effective complementary and mismatch siRNAs for silencing a geneRNAstructure: software for RNA secondary structure prediction and analysisMultilign: an algorithm to predict secondary structures conserved in multiple RNA sequencesAccurate SHAPE-directed RNA structure determinationHigh-throughput characterization of protein-RNA interactionsProgress toward in vivo use of siRNAs-IIReconsideration of in-silico siRNA design based on feature selection: a cross-platform data integration perspectiveRNA secondary structure analysis using RNAstructuresTarPicker: a method for efficient prediction of bacterial sRNA targets based on a two-step model for hybridizationA structural interpretation of the effect of GC-content on efficiency of RNA interference.Comparing artificial neural networks, general linear models and support vector machines in building predictive models for small interfering RNAs.Optimization of duplex stability and terminal asymmetry for shRNA design.Optimization of a novel biophysical model using large scale in vivo antisense hybridization data displays improved prediction capabilities of structurally accessible RNA regionsRecognition of siRNA asymmetry by TAR RNA binding protein.Quantitative prediction of miRNA-mRNA interaction based on equilibrium concentrations.siPRED: predicting siRNA efficacy using various characteristic methods.Folding and finding RNA secondary structure.Computational approaches for RNA energy parameter estimationThe role of master regulators in the metabolic/transcriptional coupling in breast carcinomasDesigning highly active siRNAs for therapeutic applications.MysiRNA-designer: a workflow for efficient siRNA design.RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transferTiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy.Computational prediction of efficient splice sites for trans-splicing ribozymes.SHAPE-directed discovery of potent shRNA inhibitors of HIV-1.siRNA Design Software for a Target Gene-Specific RNA Interference.Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide designOligoWalk: an online siRNA design tool utilizing hybridization thermodynamicsRNAstructure: Web servers for RNA secondary structure prediction and analysis.AccessFold: predicting RNA-RNA interactions with consideration for competing self-structure.Design of siRNA Therapeutics from the Molecular ScaleRational design leads to more potent RNA interference against hepatitis B virus: factors effecting silencing efficiency.RNA secondary structure prediction.Improved asymmetry prediction for short interfering RNAs.Small interfering ribonucleic acid design strategies for effective targeting and gene silencing.RNA Secondary Structure Prediction.Delivery of siRNA silencing Runx2 using a multifunctional polymer-lipid nanoparticle inhibits osteogenesis in a cell culture model of heterotopic ossificationEffect of RNA interference of the expression of HMGA2 on the proliferation and invasion ability of ACHN renal cell carcinoma cells.Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference.Selection of hyperfunctional siRNAs with improved potency and specificity
P2860
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P2860
Efficient siRNA selection using hybridization thermodynamics.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Efficient siRNA selection using hybridization thermodynamics.
@ast
Efficient siRNA selection using hybridization thermodynamics.
@en
type
label
Efficient siRNA selection using hybridization thermodynamics.
@ast
Efficient siRNA selection using hybridization thermodynamics.
@en
prefLabel
Efficient siRNA selection using hybridization thermodynamics.
@ast
Efficient siRNA selection using hybridization thermodynamics.
@en
P2860
P356
P1476
Efficient siRNA selection using hybridization thermodynamics.
@en
P2093
David H Mathews
Zhi John Lu
P2860
P304
P356
10.1093/NAR/GKM920
P407
P577
2007-12-10T00:00:00Z