The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
about
CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage responseThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayAPLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaksSpecific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNKMutations in PNKP cause microcephaly, seizures and defects in DNA repairDNA-PK: a dynamic enzyme in a versatile DSB repair pathwayOverview of base excision repair biochemistryStructure–function analysis of the 3′ phosphatase component of T4 polynucleotide kinase/phosphatasePellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and RepairStructure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamilyMechanism of repair of 5′-topoisomerase II–DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2Structure of an aprataxin–DNA complex with insights into AOA1 neurodegenerative diseaseThe Structural Basis for Substrate Recognition by Mammalian Polynucleotide Kinase 3′ PhosphataseStructural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substratesXRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediatesThe structural basis of XRCC1-mediated DNA repairStructural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathwayRole of polynucleotide kinase/phosphatase in mitochondrial DNA repairStructural and functional insights into Mimivirus ORFans.Mechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase.Nonhomologous end joining: a good solution for bad endsA fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.Mutational analysis of the 5'-OH oligonucleotide phosphate acceptor site of T4 polynucleotide kinaseStructural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complexMitochondrial DNA repair and association with aging--an updateStructural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeStructure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response.Structural dynamics in DNA damage signaling and repairPolynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitorsDual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining.Neurological disorders associated with DNA strand-break processing enzymes.Identification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF)Recognition and repair of chemically heterogeneous structures at DNA endsTidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair.Mutations in PNKP cause recessive ataxia with oculomotor apraxia type 4.Molecular underpinnings of Aprataxin RNA/DNA deadenylase function and dysfunction in neurological disease.DNA end processing by polynucleotide kinase/phosphatase.Structural basis for phosphorylation-dependent signaling in the DNA-damage response.Characterization of the 2',3' cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase
P2860
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P2860
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
@en
type
label
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
@en
prefLabel
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
@en
P2093
P1433
P1476
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
@en
P2093
C Anne Koch
Carol E Cass
Feridoun Karimi-Busheri
J N Mark Glover
Melissa L Rakovszky
Michael Weinfeld
Nina K Bernstein
Rajam S Mani
Ruth Green
P304
P356
10.1016/J.MOLCEL.2005.02.012
P577
2005-03-01T00:00:00Z