Computational analyses of the catalytic and heparin-binding sites and their interactions with glycosaminoglycans in glycoside hydrolase family 79 endo-β-D-glucuronidase (heparanase).
about
Structural and Biochemical Characterization of Glycoside Hydrolase Family 79 β-Glucuronidase from Acidobacterium capsulatumData-driven models for protein interaction and design.Recent advances in employing molecular modelling to determine the specificity of glycan-binding proteins.The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus.The potential of heparanase as a therapeutic target in cancerDBSI: DNA-binding site identifier.Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses.The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.Estimating glycosaminoglycan-protein interaction affinity: water dominates the specific antithrombin-heparin interaction.Molecular docking of heparin oligosaccharides with Hep-II heparin-binding domain of fibronectin reveals an interplay between the different positions of sulfate groups.Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease.Computational analysis of interactions in structurally available protein-glycosaminoglycan complexes.Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase.Emerging Roles of Heparanase in Viral Pathogenesis.Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues.Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus.Glycosidase Inhibition by Multivalent Presentation of Heparan Sulfate Saccharides on Bottlebrush Polymers.Cloning and bacterial expression systems for recombinant human heparanase production: Substrate specificity investigation by docking of a putative heparanase substrate.
P2860
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P2860
Computational analyses of the catalytic and heparin-binding sites and their interactions with glycosaminoglycans in glycoside hydrolase family 79 endo-β-D-glucuronidase (heparanase).
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Computational analyses of the ...... -D-glucuronidase (heparanase).
@en
type
label
Computational analyses of the ...... -D-glucuronidase (heparanase).
@en
prefLabel
Computational analyses of the ...... -D-glucuronidase (heparanase).
@en
P2860
P356
P1433
P1476
Computational analyses of the ...... β-D-glucuronidase (heparanase)
@en
P2093
Christopher R Parish
Craig Freeman
P2860
P356
10.1093/GLYCOB/CWR095
P577
2011-07-11T00:00:00Z